SCHEMBL5677296

SCHEMBL5677296

C1CNC(NCCNC2=NCCN2)=N1

nearest known ligand 0.79

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CXCR4 P61073 3/20 0.79
APOBEC3A P31941 1/20 0.73
APOBEC3G Q9HC16 1/20 0.73
ADRA2A P08913 13/20 0.48
ADRA2B P18089 13/20 0.48
ADRA2C P18825 13/20 0.48
WDR5 P61964 1/20 0.46
PTGIR P43119 1/20 0.44
ADRA1D P25100 3/20 0.41
ADRA1A P35348 3/20 0.41
ADRA1B P35368 3/20 0.41
LMNA P02545 2/20 0.41
MEN1 O00255 1/20 0.41
SLC22A1 O15245 1/20 0.41
SLC22A3 O75751 1/20 0.41
HTR1A P08908 1/20 0.41
CYP2D6 P10635 1/20 0.41
CYP2C9 P11712 1/20 0.41
HRH2 P25021 1/20 0.41
CYP2C19 P33261 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Bromide SCHEMBL8624628 0.98 CXCR4 (0.76) CXCR4APOBEC3AAPOBEC3GADRA2AADRA2B
SCHEMBL12132035 0.89 CXCR4 (0.66) CXCR4APOBEC3AAPOBEC3GADRA2AADRA2B
SCHEMBL6301909 0.88 CXCR4 (0.75) CXCR4APOBEC3AAPOBEC3GADRA2AADRA2B
SCHEMBL12966337 0.87
SCHEMBL13512431 0.87
Hydrochloric Acid SCHEMBL7541441 0.86 CXCR4 (0.72) CXCR4APOBEC3AAPOBEC3GADRA2AADRA2B
SCHEMBL12145482 0.83 CXCR4 (0.63) CXCR4APOBEC3AAPOBEC3GADRA2AADRA2B
SCHEMBL2492454 0.83 CXCR4 (0.75) CXCR4APOBEC3AAPOBEC3GADRA2AADRA2B
SCHEMBL13509984 0.83 CXCR4 (0.63) CXCR4APOBEC3AAPOBEC3GADRA2AADRA2B
SCHEMBL25213248 0.83 APOBEC3A (0.59) CXCR4APOBEC3AAPOBEC3GADRA2AADRA2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0708086-B1 Bisguanidine salts and a method for releasing a base using the same salts FUJI PHOTO FILM CO LTD (JP) 1998-05-20 EP claimed
US-5728879-A HEAT SENSITIVE ELEMENTS FOR RECORDING AND FORMING IMAGES FUJI PHOTO FILM CO., LTD. (JP) 1998-03-17 US claimed
EP-0708086-A1 Bisguanidine salts and a method for releasing a base using the same salts FUJI PHOTO FILM CO., LTD. (JP) 1996-04-24 EP claimed
JP-8169870-A None JP disclosed
US-7029835-B2 Photothermographic element comprising improved base precursors and methods for their use EASTMAN KODAK COMPANY (US) 2006-04-18 US disclosed
US-6974662-B2 Thermal base precursors EASTMAN KODAK COMPANY (US) 2005-12-13 US disclosed
WO-2005043238-A1 THERMAL BASE PRECURSORS EASTMAN KODAK COMPANY (US) 2005-05-12 WO disclosed
US-20050032009-A1 Thermal base precursors EASTMAN KODAK COMPANY 2005-02-10 US disclosed
US-20040185352-A1 Photothermographic element comprising improved base precursors and methods for their use CARESTREAM HEALTH, INC. 2004-09-23 US disclosed
US-6746807-B1 COLOR PHOTOTHERMOGRAPHIC IMAGING ELEMENT COMPRISING FILTER DYE WHICH UNDERGOES EFFICIENT AND IRREVERSIBLE THERMAL BLEACHING DURING THERMAL PROCESSING AT LOWER TEMPERATURES EASTMAN KODAK COMPANY 2004-06-08 US disclosed
EP-1422549-A1 Photothermographic elements containing thermally bleachable filter dye compositions comprising benzothiazine-dioxide arylidene dyes and base precursors EASTMAN KODAK COMPANY (US) 2004-05-26 EP disclosed
US-20040096758-A1 THERMALLY BLEACHABLE FILTER DYE COMPOSITIONS COMPRISING BENZOTHIAZINE-DIOXIDE ARYLIDENE DYES AND BASE PRECURSORS FOR USE IN A PHOTOTHERMOGRAPHIC ELEMENT EASTMAN KODAK COMPANY 2004-05-20 US disclosed
US-6730462-B1 Thermally bleachable yellow filter dye compositions barbituric acid arylidene dyes and base precursors EASTMAN KODAK COMPANY 2004-05-04 US disclosed
US-6699651-B1 THERMALLY BLEACHABLE FILTER DYE COMPOSITIONS COMPRISING A BASE PRECURSOR THAT IS THE SALT OF AN ORGANIC BASE WITH AN ARYLSULFONYLACETIC ACID EASTMAN KODAK COMPANY 2004-03-02 US disclosed
EP-0708086-B1 Bisguanidine salts and a method for releasing a base using the same salts FUJI PHOTO FILM CO LTD (JP) 1998-05-20 EP disclosed
US-5728879-A HEAT SENSITIVE ELEMENTS FOR RECORDING AND FORMING IMAGES FUJI PHOTO FILM CO., LTD. (JP) 1998-03-17 US disclosed
US-5728879-A HEAT SENSITIVE ELEMENTS FOR RECORDING AND FORMING IMAGES FUJI PHOTO FILM CO., LTD. (JP) 1998-03-17 US disclosed
JP-H08169870-A BISGUANIDINE SALT FUJI PHOTO FILM CO LTD 1996-07-02 JP disclosed
EP-0708086-A1 Bisguanidine salts and a method for releasing a base using the same salts FUJI PHOTO FILM CO., LTD. (JP) 1996-04-24 EP disclosed
EP-0708086-A1 Bisguanidine salts and a method for releasing a base using the same salts FUJI PHOTO FILM CO., LTD. (JP) 1996-04-24 EP disclosed