Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | MAPT | P10636 | 5/20 | 0.43 |
| ▸ | HTT | P42858 | 3/20 | 0.43 |
| ▸ | PKM | P14618 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | NAMPT | P43490 | 1/20 | 0.42 |
| ▸ | REV1 | Q9UBZ9 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7603987 | 0.84 | NAMPT (0.53) | NPSR1USP2HSD17B10ALDH1A1MAPT | |
| SCHEMBL7607418 | 0.83 | NPSR1 (0.49) | NPSR1USP2HSD17B10ALDH1A1MAPT | |
| SCHEMBL20976555 | 0.81 | ALDH1A1 (0.47) | NPSR1USP2HSD17B10ALDH1A1MAPT | |
| SCHEMBL20976519 | 0.81 | ALDH1A1 (0.47) | NPSR1USP2HSD17B10ALDH1A1MAPT | |
| SCHEMBL7607167 | 0.80 | ALDH1A1 (0.51) | NPSR1USP2HSD17B10ALDH1A1MAPT | |
| SCHEMBL20976500 | 0.80 | ALDH1A1 (0.48) | NPSR1USP2HSD17B10ALDH1A1MAPT | |
| SCHEMBL19186933 | 0.79 | REV1 (0.54) | NPSR1USP2HSD17B10ALDH1A1MAPT | |
| SCHEMBL11996 | 0.79 | HTT (0.60) | HSD17B10ALDH1A1MAPTHTTPKM | |
| SCHEMBL7603082 | 0.79 | ALDH1A1 (0.48) | NPSR1ALDH1A1MAPTHTTLMNA | |
| SCHEMBL7603092 | 0.79 | ALDH1A1 (0.48) | NPSR1USP2HSD17B10ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011050210-A1 | METHODS AND COMPOSITIONS FOR CELL-PROLIFERATION-RELATED DISORDERS | AGIOS PHARMACEUTICALS, INC. (US) | 2011-04-28 | — | — | WO | disclosed |