Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | LDHA | P00338 | 1/20 | 0.42 |
| ▸ | SRR | Q9GZT4 | 1/20 | 0.42 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | KDM6B | O15054 | 1/20 | 0.36 |
| ▸ | KDM5C | P41229 | 1/20 | 0.36 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.36 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.36 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.36 |
| ▸ | ECE1 | P42892 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL918553 | 0.77 | HDAC3 (0.35) | FOLH1KDM4EKDM6BKDM5CEGLN1 | |
| SCHEMBL18504330 | 0.76 | ALOX15 (0.44) | ALOX15HSD17B10LDHASRREGLN1 | |
| SCHEMBL5176374 | 0.76 | ALOX15 (0.44) | ALOX15HSD17B10LDHASRRKDM4E | |
| SCHEMBL5512160 | 0.76 | ALOX15 (0.44) | ALOX15HSD17B10LDHASRRKDM4E | |
| SCHEMBL30208621 | 0.74 | ALOX15 (0.54) | ALOX15HSD17B10LDHASRRKDM4E | |
| SCHEMBL14342206 | 0.73 | — | — | |
| Itaconate SCHEMBL21523 | 0.73 | — | — | |
| Itaconate SCHEMBL286967 | 0.73 | ALOX15 (0.75) | ALOX15HSD17B10LDHASRRKDM4E | |
| Itaconate SCHEMBL29886131 | 0.73 | — | — | |
| SCHEMBL1767666 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2389342-B1 | SURFACE-MODIFIED ZIRCONIA NANOPARTICLES | 3M INNOVATIVE PROPERTIES CO (US) | 2020-11-04 | — | — | EP | disclosed |
| US-8829079-B2 | Surface-modified zirconia nanoparticles | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2014-09-09 | — | — | US | disclosed |
| US-20110288215-A1 | SURFACE-MODIFIED ZIRCONIA NANOPARTICLES | 3M INNOVATIVE PROPERTIES COMPANY | 2011-11-24 | — | — | US | disclosed |
| WO-2010085427-A1 | SURFACE-MODIFIED ZIRCONIA NANOPARTICLES | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2010-07-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110288215-A1 | SURFACE-MODIFIED ZIRCONIA NANOPARTICLES | ZKSCAN2, CD63, HDAC9 | ALOX15 3256/4885HSD17B10 3455/4885LDHA 676/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.