SCHEMBL5176374

SCHEMBL5176374

C=C(CC(=O)O)C(=O)NC

nearest known ligand 0.55

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 1/20 0.44
HSD17B10 Q99714 1/20 0.44
LDHA P00338 1/20 0.40
SRR Q9GZT4 1/20 0.40
EGLN1 Q9GZT9 3/20 0.32
KDM4E B2RXH2 2/20 0.32
KDM5C P41229 2/20 0.32
PHF8 Q9UPP1 2/20 0.32
KDM2A Q9Y2K7 2/20 0.32
KDM6B O15054 1/20 0.32
FFAR3 O14843 1/20 0.32
TGFBR1 P36897 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11160343 0.80
SCHEMBL11436554 0.79 MCL1 (0.37)
SCHEMBL7166020 0.78 LMNA (0.35)
SCHEMBL5176368 0.77 TDP1 (0.33)
SCHEMBL5673103 0.76
SCHEMBL12148282 0.76 ALOX15 (0.46) ALOX15HSD17B10LDHASRREGLN1
SCHEMBL11115709 0.76
Itaconate SCHEMBL5875036 0.76 ALOX15 (0.65) ALOX15HSD17B10LDHASRREGLN1
Itaconate SCHEMBL5875042 0.76 ALOX15 (0.65) ALOX15HSD17B10LDHASRREGLN1
SCHEMBL5174585 0.75 ALOX15 (0.41) ALOX15HSD17B10LDHASRREGLN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-2129200-A None JP disclosed
US-20130183521-A1 TRANSLUCENT LIGHT-SHIELDING TAPE NITTO DENKO CORPORATION (JP) 2013-07-18 US disclosed
US-8057952-B2 Polymer electrolyte membrane, method of manufacturing the same and fuel cell including the polymer electrolyte membrane SAMSUNG SDI CO., LTD. (KR) 2011-11-15 US disclosed
US-8057952-B2 Polymer electrolyte membrane, method of manufacturing the same and fuel cell including the polymer electrolyte membrane SAMSUNG SDI CO., LTD. (KR) 2011-11-15 US disclosed
US-20070202375-A1 Polymer electrolyte membrane, method of manufacturing the same and fuel cell including the polymer electrolyte membrane SAMSUNG SDI CO., LTD. (KR) 2007-08-30 US disclosed
US-20070202375-A1 Polymer electrolyte membrane, method of manufacturing the same and fuel cell including the polymer electrolyte membrane SAMSUNG SDI CO., LTD. (KR) 2007-08-30 US disclosed
EP-1602481-B1 Lithographic printing plate precursor FUJIFILM CORP (JP) 2007-05-30 EP disclosed
EP-1203659-B1 Lithographic printing plate precursor FUJI PHOTO FILM CO LTD (JP) 2006-05-17 EP disclosed
EP-1602481-A1 Lithographic printing plate precursor FUJI PHOTO FILM CO., LTD. (JP) 2005-12-07 EP disclosed
EP-1371500-B1 Lithographic printing plate precursor FUJI PHOTO FILM CO LTD (JP) 2005-09-28 EP disclosed
EP-1371500-A1 Lithographic printing plate precursor FUJI PHOTO FILM CO., LTD. (JP) 2003-12-17 EP disclosed
US-20030190553-A1 Support with hydrophilic surface; multilayer; latex layer and ink receiver FUJIFILM CORPORATION (JP) 2003-10-09 US disclosed
US-6509132-B1 Comprises an ink-receptive image area for receiving ink during the printing process and a hydrophilic non-image area for receiving fountain solution FUJI PHOTO FILM CO., LTD. (JP) 2003-01-21 US disclosed
US-6455224-B1 SUPPORT WITH HYDROPHILIC SURFACE AND PHOTOSENSITIVE LAYER CONTAINING INFRARED ABSORBENT WHICH CHANGES FROM HYDROPHILIC TO HYDROPHOBIC BY HEAT AND HYDROPHILIC POLYMER HAVING FUNCTIONAL GROUP RENDERING LAYER WATER DEVELOPABLE FUJI PHOTO FILM CO., LTD. (JP) 2002-09-24 US disclosed
US-20020068241-A1 Lithographic printing plate precursor FUJIFILM CORPORATION (JP) 2002-06-06 US disclosed
EP-1203659-A2 Lithographic printing plate precursor FUJI PHOTO FILM CO., LTD. (JP) 2002-05-08 EP disclosed
EP-1136281-A1 Lithographic printing plate precursor FUJI PHOTO FILM CO., LTD. (JP) 2001-09-26 EP disclosed
EP-1048457-A2 Lithographic printing plate precursor FUJI PHOTO FILM CO., LTD. (JP) 2000-11-02 EP disclosed
EP-1031414-A1 Lithographic printing plate precursor FUJI PHOTO FILM CO., LTD. (JP) 2000-08-30 EP disclosed
JP-H02129200-A SOLID PHASE SYNTHESIS OF PEPTIDE EXPANSION SCIENCE EXPANSIA:SOC 1990-05-17 JP disclosed