SCHEMBL12148384

SCHEMBL12148384

c1ccc(-c2cc(-c3cc(-c4ccccn4)cc(-c4ccccn4)c3)cc(-c3ccccc3)n2)cc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ KDM4E B2RXH2 4/20 0.52
▸ CCR1 P32246 3/20 0.52
▸ CCR5 P51681 3/20 0.52
▸ CCR8 P51685 3/20 0.52
▸ LMNA P02545 3/20 0.52
▸ SMN1; SMN2 Q16637 3/20 0.52
▸ TDP1 Q9NUW8 2/20 0.52
▸ TP53 P04637 2/20 0.52
▸ MAPK1 P28482 2/20 0.52
▸ L3MBTL1 Q9Y468 2/20 0.52
▸ ALPL P05186 1/20 0.52
▸ HSP90AA1 P07900 1/20 0.52
▸ ALPI P09923 1/20 0.52
▸ ALPG P10696 1/20 0.52
▸ ALOX15 P16050 1/20 0.52
▸ HTT P42858 1/20 0.52
▸ RAB9A P51151 4/20 0.50
▸ CYP19A1 P11511 1/20 0.50
▸ MEN1 O00255 1/20 0.50
▸ KMT2A Q03164 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12148388 0.98 CYP19A1 (0.53) KDM4ECCR1CCR5CCR8LMNA
SCHEMBL17343429 0.96 CYP19A1 (0.51) KDM4ECCR1CCR5CCR8LMNA
SCHEMBL18961086 0.96 CYP19A1 (0.51) KDM4ECCR1CCR5CCR8LMNA
SCHEMBL17932367 0.94 CYP19A1 (0.53) KDM4ECCR1CCR5CCR8LMNA
SCHEMBL17367836 0.94 CYP19A1 (0.53) KDM4ECCR1CCR5CCR8LMNA
SCHEMBL17343430 0.94 KDM4E (0.54) KDM4ECCR1CCR5CCR8LMNA
SCHEMBL24398187 0.93 TGFBR1 (0.51) KDM4ECCR1CCR5CCR8LMNA
SCHEMBL17932365 0.93 KDM4E (0.50) KDM4ECCR1CCR5CCR8LMNA
SCHEMBL31336971 0.92 CCR1 (0.58) KDM4ECCR1CCR5CCR8LMNA
SCHEMBL17343426 0.92 KDM4E (0.57) KDM4ECCR1CCR5CCR8LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9978955-B2 Organic light-emitting device SAMSUNG DISPLAY CO., LTD. (KR) 2018-05-22 — — US disclosed
US-9978955-B2 Organic light-emitting device SAMSUNG DISPLAY CO., LTD. (KR) 2018-05-22 — — US disclosed
US-9680108-B2 Organic light-emitting device SAMSUNG DISPLAY CO., LTD. (KR) 2017-06-13 — — US disclosed
US-9680108-B2 Organic light-emitting device SAMSUNG DISPLAY CO., LTD. (KR) 2017-06-13 — — US disclosed
US-20160218297-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2016-07-28 — — US disclosed
US-20160020404-A1 ORGANIC LIGHT EMITTING DIODE AND ORGANIC LIGHT EMITTING DISPLAY DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2016-01-21 — — US disclosed
US-20160020404-A1 ORGANIC LIGHT EMITTING DIODE AND ORGANIC LIGHT EMITTING DISPLAY DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2016-01-21 — — US disclosed
US-20150380662-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2015-12-31 — — US disclosed
US-20150380662-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2015-12-31 — — US disclosed
US-20150364693-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2015-12-17 — — US disclosed
US-20150364693-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2015-12-17 — — US disclosed
US-8435648-B2 Pyridinylene ring compound for organic optoelectronic device, organic light emitting diode including the same and display including the organic light emitting diode CHEIL INDUSTRIES, INC. (KR) 2013-05-07 — — US disclosed
US-8435648-B2 Pyridinylene ring compound for organic optoelectronic device, organic light emitting diode including the same and display including the organic light emitting diode CHEIL INDUSTRIES, INC. (KR) 2013-05-07 — — US disclosed
US-20110284832-A1 COMPOUND FOR ORGANIC OPTOELECTRONIC DEVICE, ORGANIC LIGHT EMITTING DIODE INCLUDING THE SAME AND DISPLAY INCLUDING THE ORGANIC LIGHT EMITTING DIODE CHEIL INDUSTRIES, INC. (KR) 2011-11-24 — — US disclosed
US-20110284832-A1 COMPOUND FOR ORGANIC OPTOELECTRONIC DEVICE, ORGANIC LIGHT EMITTING DIODE INCLUDING THE SAME AND DISPLAY INCLUDING THE ORGANIC LIGHT EMITTING DIODE CHEIL INDUSTRIES, INC. (KR) 2011-11-24 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110284832-A1 COMPOUND FOR ORGANIC OPTOELECTRONIC DEVICE, ORGANIC LIGHT EMITTING DIODE INCLUDING THE SAME AND DISPLAY INCLUDING THE ORGANIC LIGHT EMITTING DIODE OR10J3, AOX1, OR51E2 KDM4E 2788/4885CCR1 2163/4885CCR5 3382/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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