Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT5 | O14744 | 17/20 | 0.45 |
| ▸ | WDR77 | Q9BQA1 | 16/20 | 0.45 |
| ▸ | ADK | P55263 | 1/20 | 0.43 |
| ▸ | METTL3 | Q86U44 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12150846 | 0.92 | PRMT5 (0.46) | PRMT5WDR77ADKMETTL3 | |
| SCHEMBL12746923 | 0.91 | PRMT5 (0.47) | PRMT5WDR77ADK | |
| SCHEMBL12150821 | 0.91 | PRMT5 (0.47) | PRMT5WDR77ADK | |
| SCHEMBL12150791 | 0.88 | PRMT5 (0.52) | PRMT5WDR77ADK | |
| SCHEMBL12746902 | 0.88 | PRMT5 (0.52) | PRMT5WDR77ADK | |
| SCHEMBL12150828 | 0.85 | PRMT5 (0.46) | PRMT5WDR77ADKMETTL3 | |
| SCHEMBL12746926 | 0.85 | PRMT5 (0.46) | PRMT5WDR77ADKMETTL3 | |
| SCHEMBL16198971 | 0.85 | PRMT5 (0.47) | PRMT5WDR77ADKMETTL3 | |
| SCHEMBL12746927 | 0.84 | PRMT5 (0.48) | PRMT5WDR77ADK | |
| SCHEMBL12150831 | 0.84 | PRMT5 (0.48) | PRMT5WDR77ADK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110288053-A1 | ANTIVIRAL PHOSPHONATE ANALOGS | GILEAD SCIENCES, INC. (US) | 2011-11-24 | — | — | US | disclosed |
| US-20110071101-A1 | Nucleoside Phosphonate Analogs | BOOJAMRA CONSTANTINE G | 2011-03-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110071101-A1 | Nucleoside Phosphonate Analogs | TYMP, PNP, NUDT1 | PRMT5 1930/4885WDR77 3393/4885ADK 131/4885 |
| US-20110288053-A1 | ANTIVIRAL PHOSPHONATE ANALOGS | TYMP, ITPA, PNP | PRMT5 2581/4885WDR77 1899/4885ADK 341/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.