Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT5 | O14744 | 16/20 | 0.47 |
| ▸ | WDR77 | Q9BQA1 | 14/20 | 0.47 |
| ▸ | ADK | P55263 | 1/20 | 0.45 |
| ▸ | METTL3 | Q86U44 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16198970 | 0.92 | PRMT5 (0.48) | PRMT5WDR77ADKMETTL3 | |
| SCHEMBL16198962 | 0.85 | PRMT5 (0.50) | PRMT5WDR77ADKMETTL3 | |
| SCHEMBL12150874 | 0.85 | PRMT5 (0.45) | PRMT5WDR77ADKMETTL3 | |
| SCHEMBL12154743 | 0.85 | ADK (0.53) | PRMT5WDR77ADKMETTL3 | |
| SCHEMBL12150870 | 0.85 | ADK (0.53) | PRMT5WDR77ADKMETTL3 | |
| SCHEMBL475133 | 0.85 | ADK (0.53) | PRMT5WDR77ADKMETTL3 | |
| SCHEMBL31154634 | 0.79 | PRMT5 (0.56) | PRMT5WDR77ADK | |
| SCHEMBL12154683 | 0.77 | ADK (0.56) | PRMT5WDR77ADKMETTL3 | |
| SCHEMBL731889 | 0.77 | ADK (0.56) | PRMT5WDR77ADKMETTL3 | |
| SCHEMBL6841559 | 0.77 | ADK (0.56) | PRMT5WDR77ADKMETTL3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8871785-B2 | Antiviral phosphonate analogs | GILEAD SCIENCES, INC. (US) | 2014-10-28 | — | — | US | disclosed |