Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 3/20 | 0.49 |
| ▸ | TSHR | P16473 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | PKM | P14618 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | PPARG | P37231 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | MGLL | Q99685 | 2/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | LTA4H | P09960 | 2/20 | 0.39 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14397616 | 0.92 | TDP1 (0.59) | TDP1TP53TSHRALDH1A1MAPT | |
| SCHEMBL15345203 | 0.88 | TDP1 (0.54) | TDP1TP53TSHRALDH1A1MAPT | |
| SCHEMBL12516201 | 0.88 | TDP1 (0.54) | TDP1TP53TSHRALDH1A1MAPT | |
| SCHEMBL194748 | 0.87 | TDP1 (0.66) | TDP1TP53TSHRALDH1A1MAPT | |
| SCHEMBL15246816 | 0.87 | TDP1 (0.66) | TDP1TP53TSHRALDH1A1MAPT | |
| SCHEMBL17902752 | 0.87 | TDP1 (0.66) | TDP1TP53TSHRALDH1A1MAPT | |
| SCHEMBL16527790 | 0.87 | TDP1 (0.66) | TDP1TP53TSHRALDH1A1MAPT | |
| SCHEMBL18627825 | 0.86 | ALDH1A1 (0.54) | TDP1TP53TSHRALDH1A1MAPT | |
| SCHEMBL17826371 | 0.86 | TDP1 (0.56) | TDP1TP53TSHRALDH1A1MAPT | |
| SCHEMBL16153915 | 0.85 | TDP1 (0.51) | TDP1TP53TSHRALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2385078-A1 | Dendritic polymers with enhanced amplification and interior functionality | Dendritic Nanotechnologies Inc. (US) | 2011-11-09 | — | — | EP | disclosed |
| US-7981444-B2 | Dendritic polymers with enhanced amplification and interior functionality | DENDRITIC NANOTECHNOLOGIES, INC. (US) | 2011-07-19 | — | — | US | disclosed |
| US-20070244296-A1 | Dendritic Polymers with Enhanced Amplification and Interior Functionality | DENDRITIC NANOTECHNOLOGIES, INC. (US) | 2007-10-18 | — | — | US | disclosed |