Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTAFR | P25105 | 18/20 | 0.69 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.45 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Israpafant SCHEMBL8792967 | 1.00 | PTAFR (0.69) | PTAFROPRK1PDE4DCYP3A4ALOX15 | |
| Israpafant SCHEMBL121588 | 1.00 | PTAFR (0.69) | PTAFROPRK1PDE4DCYP3A4ALOX15 | |
| Israpafant SCHEMBL30733966 | 1.00 | PTAFR (0.69) | PTAFROPRK1PDE4DCYP3A4ALOX15 | |
| Israpafant SCHEMBL8794591 | 0.99 | PTAFR (0.68) | PTAFROPRK1PDE4DCYP3A4ALOX15 | |
| SCHEMBL9374585 | 0.92 | PTAFR (0.58) | PTAFROPRK1PDE4DCYP3A4ALOX15 | |
| Israpafant SCHEMBL8792589 | 0.90 | PTAFR (0.57) | PTAFROPRK1PDE4DCYP3A4ALOX15 | |
| SCHEMBL8878479 | 0.90 | PTAFR (0.67) | PTAFROPRK1PDE4DCYP3A4ALOX15 | |
| SCHEMBL9374425 | 0.89 | PTAFR (0.64) | PTAFROPRK1PDE4DCYP3A4ALOX15 | |
| SCHEMBL8877687 | 0.89 | PTAFR (0.57) | PTAFROPRK1PDE4DCYP3A4ALOX15 | |
| SCHEMBL8126816 | 0.89 | PTAFR (0.66) | PTAFROPRK1PDE4DCYP3A4ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 559 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1962797-B2 | POWDER COMPOSITIONS FOR INHALATION | JAGOTEC AG (CH) | 2024-05-29 | — | — | EP | claimed |
| EP-1962797-B1 | POWDER COMPOSITIONS FOR INHALATION | JAGOTEC AG (CH) | 2020-10-28 | — | — | EP | claimed |
| EP-3354263-A1 | DRY POWDER FORMULATIONS | Jagotec AG (CH) | 2018-08-01 | — | — | EP | claimed |
| EP-3275435-A1 | DRY POWDER FORMULATIONS | Jagotec AG (CH) | 2018-01-31 | — | — | EP | claimed |
| EP-1689360-B1 | DRY POWDER FORMULATIONS | JAGOTEC AG (CH) | 2017-08-23 | — | — | EP | claimed |
| US-9016221-B2 | Surface topographies for non-toxic bioadhesion control | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2015-04-28 | — | — | US | claimed |
| US-20150037425-A1 | POWDER COMPOSITIONS FOR INHALATION | JAGOTEC AG (CH) | 2015-02-05 | — | — | US | claimed |
| CN-104224720-A | DRY POWDER FORMULATIONS | JAGOTEC AG | 2014-12-24 | — | — | CN | claimed |
| CN-101325945-B | Powder compositions for inhalation | JAGOTEC AG | 2014-11-26 | — | — | CN | claimed |
| CN-1878537-B | Dry powder formulation, method of preparing the same and dry powder inhaler using the same | JAGOTEC AG | 2014-08-20 | — | — | CN | claimed |
| EP-1283036-A1 | Dry powder for inhalation | JAGO RESEARCH AG (CH) | 2003-02-12 | — | — | EP | claimed |
| WO-2002079778-A2 | IN VIVO DELIVERY METHODS AND COMPOSITIONS | RHEOLOGICS, INC. (US) | 2002-10-10 | — | — | WO | claimed |
| WO-2002043806-A2 | IN VIVO DELIVERY METHODS AND COMPOSITIONS | RHEOLOGICS, INC (US) | 2002-06-06 | — | — | WO | claimed |
| US-20020061835-A1 | Administering a drug to a human which is pharmaceutically effective to regulate at least one of the blood parameters used to adjust distribution of the drug through the bloodstream | RHEOLOGICS, INC. | 2002-05-23 | — | — | US | claimed |
| US-20020032149-A1 | Monitoring blood flow parameter of bloodstream, administering substance to organism such that an amount of substance enters bloodstream; distributing portion of amount ofsubstance target within organism | RHEOLOGICS, INC. | 2002-03-14 | — | — | US | claimed |
| CN-1326341-A | Dry powder for inhalation | JIG RES AG (CH) | 2001-12-12 | — | — | CN | claimed |
| US-20010044584-A1 | In vivo delivery methods and compositions | RHEOLOGICS, INC. | 2001-11-22 | — | — | US | claimed |
| EP-1131059-A1 | DRY POWDER FOR INHALATION | JAGO RESEARCH AG (CH) | 2001-09-12 | — | — | EP | claimed |
| EP-1004309-A1 | ISRAPAFANT-CONTAINING WATER-BASE PREPARATIONS | Senju Pharmaceutical Co., Ltd. (JP) | 2000-05-31 | — | — | EP | claimed |
| WO-2000028979-A1 | DRY POWDER FOR INHALATION | JAGO RESEARCH AG (CH) | 2000-05-25 | — | — | WO | claimed |