SCHEMBL121635

SCHEMBL121635

ClCCN(CCCl)c1ccccc1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
EGFR P00533 4/20 0.58
ERBB2 P04626 4/20 0.58
ALDH1A1 P00352 4/20 0.47
SMN1; SMN2 Q16637 3/20 0.47
HIF1A Q16665 3/20 0.47
LMNA P02545 3/20 0.47
MAPT P10636 3/20 0.47
NFKB1 P19838 2/20 0.47
THPO P40225 2/20 0.47
PMP22 Q01453 2/20 0.47
TSHR P16473 2/20 0.47
GMNN O75496 1/20 0.47
CYP2D6 P10635 1/20 0.47
GABRA1 P14867 1/20 0.47
GABRA2 P47869 1/20 0.47
GABRB2 P47870 1/20 0.47
SLCO1B3 Q9NPD5 1/20 0.47
CYP3A4 P08684 3/20 0.46
ALOX15 P16050 2/20 0.46
KMT2A Q03164 2/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13338131 0.89 EGFR (0.54) EGFRERBB2ALDH1A1SMN1; SMN2HIF1A
SCHEMBL10473426 0.89 EGFR (0.54) EGFRERBB2ALDH1A1SMN1; SMN2HIF1A
SCHEMBL11693160 0.87 ALDH1A1 (0.51) EGFRERBB2ALDH1A1SMN1; SMN2HIF1A
SCHEMBL11411350 0.87 EGFR (0.57) EGFRERBB2ALDH1A1SMN1; SMN2HIF1A
Acetic Acid SCHEMBL20565475 0.87 EGFR (0.66) EGFRERBB2ALDH1A1SMN1; SMN2HIF1A
SCHEMBL479209 0.86 TSHR (0.55) EGFRERBB2ALDH1A1SMN1; SMN2MAPT
SCHEMBL1438703 0.85 EGFR (0.55) EGFRERBB2ALDH1A1SMN1; SMN2HIF1A
SCHEMBL11690263 0.84 TSHR (0.59) EGFRERBB2ALDH1A1SMN1; SMN2HIF1A
SCHEMBL11441597 0.84 USP2 (0.46) EGFRERBB2ALDH1A1SMN1; SMN2HIF1A
SCHEMBL10454442 0.83 ALDH1A1 (0.51) EGFRERBB2ALDH1A1SMN1; SMN2HIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 466 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4447934-B1 CARRIER AS A MULTIFUNCTIONAL SYSTEM LIFESOME THERAPEUTICS SL (ES) 2025-08-06 EP claimed
EP-4074735-B1 CONDITIONALLY ACTIVE CHIMERIC ANTIGEN RECEPTORS FOR MODIFIED T-CELLS BIOATLA INC (US) 2025-05-21 EP claimed
CN-110423212-B Hydroxy indole carboxylic acid-based inhibitors of SHP2 美国印第安纳大学研究和技术公司 2023-05-09 CN claimed
EP-3210627-B1 CONJUGATES OF CELL BINDING MOLECULES WITH CYTOTOXIC AGENTS HANGZHOU DAC BIOTECH CO LTD (CN) 2022-12-21 EP claimed
EP-3186284-B1 CONDITIONALLY ACTIVE CHIMERIC ANTIGEN RECEPTORS FOR MODIFIED T-CELLS BIOATLA INC (US) 2022-04-06 EP claimed
US-20220073910-A1 A Cross-Linking Approach to Map Small Molecule-RNA Binding Sites in Cells NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2022-03-10 US claimed
WO-2020167811-A1 A CROSS-LINKING APPROACH TO MAP SMALL MOLECULE-RNA BINDING SITES IN CELLS THE SCRIPPS RESEARCH INSTITUTE (US) 2020-08-20 WO claimed
CN-109438321-A A kind of tryptophan derivative and its preparation method and application 南京友怡医药科技有限公司 2019-03-08 CN claimed
US-20180044362-A1 PLATINUM PRODRUGS AND METHODS OF MAKING AND USING THEREOF UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. 2018-02-15 US claimed
WO-2016144889-A1 PLATINUM PRODRUGS AND METHODS OF MAKING AND USING THEREOF UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) 2016-09-15 WO claimed
US-20030216871-A1 Calculating a characteristic property of a molecule by correlation analysis ICE ENERGY, INC. 2003-11-20 US claimed
US-20030129617-A1 Calculating a biological characteristic property of a molecule by correlation analysis PROLOG CAPITAL A, L.P. 2003-07-10 US claimed
WO-2003012439-A2 METHOD FOR CALCULATING A BIOLOGICAL CHARACTERISTIC PROPERTY OF A MOLECULE BY CORRELATION ANALYSIS APT THERAPEUTICS, INC. (US) 2003-02-13 WO claimed
WO-2003012676-A2 METHOD FOR CALCULATING A CHARACTERISTIC PROPERTY OF A MOLECULE BY CORRELATION ANALYSIS APT THERAPEUTICS, INC. (US) 2003-02-13 WO claimed
EP-0520226-B2 Halogen scavenger composition ST CHEMICAL CO LTD (JP) 2000-10-11 EP claimed
US-5968933-A ANTITUMOR AGENTS AND BINDING DNA FOR MUTAGENESIS AUCKLAND DIVISION CANCER SOCIETY OF NEW ZEALAND INC. (NZ) 1999-10-19 US claimed
EP-0777656-A4 NOVEL DNA-TARGETED ALKYLATING AGENTS CANCER SOC AUCKLAND DIV NZ INC (NZ) 1998-04-15 EP claimed
EP-0777656-A1 NOVEL DNA-TARGETED ALKYLATING AGENTS AUCKLAND DIVISION CANCER SOCIETY OF NEW ZEALAND (INCORPORATED) (NZ) 1997-06-11 EP claimed
WO-1996006831-A1 NOVEL DNA-TARGETED ALKYLATING AGENTS AUCKLAND DIVISION CANCER SOCIETY OF NEW ZEALAND INC. (NZ) 1996-03-07 WO claimed
US-4439380-A Photopolymerizable composition, especially for dental purposes ETABLISSEMENT DENTAIRE IVOCLAR (LI) 1984-03-27 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180044362-A1 PLATINUM PRODRUGS AND METHODS OF MAKING AND USING THEREOF MGMT, DPYD, OGG1 EGFR 1196/4885ERBB2 1874/4885ALDH1A1 340/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.