SCHEMBL12166328

SCHEMBL12166328

c1ccc(-c2ncnc(-c3cc(-c4ncnc(-c5ccccc5)n4)cc(C4(c5cc(-c6ncnc(-c7ccccc7)n6)cc(-c6ncnc(-c7ccccc7)n6)c5)c5ccccc5Oc5ccccc54)c3)n2)cc1

nearest known ligand 0.33

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.33
MAPT P10636 2/20 0.33
KMT2A Q03164 2/20 0.33
KDM4E B2RXH2 1/20 0.33
NPC1 O15118 1/20 0.33
POLB P06746 1/20 0.33
RAB9A P51151 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.32
HTT P42858 1/20 0.31
ALDH1A1 P00352 1/20 0.31
HPGD P15428 1/20 0.31
CSF1R P07333 1/20 0.31
PDGFRB P09619 1/20 0.31
GSK3A P49840 1/20 0.31
CDK9 P50750 1/20 0.31
CDK5 Q00535 1/20 0.31
ACVR1 Q04771 1/20 0.31
CDK5R1 Q15078 1/20 0.31
TAOK1 Q7L7X3 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12166322 0.93 KDM4E (0.31) MEN1MAPTKMT2AKDM4ENPC1
SCHEMBL12166333 0.93 L3MBTL1 (0.38) MEN1MAPTKMT2AKDM4ENPC1
SCHEMBL12166337 0.91 BACE1 (0.31) MEN1MAPTKMT2AKDM4ENPC1
SCHEMBL12166345 0.90 KMT2A (0.32) MEN1MAPTKMT2AKDM4ENPC1
SCHEMBL12166323 0.88 L3MBTL1 (0.33) MEN1MAPTKMT2APOLBL3MBTL1
SCHEMBL12166330 0.86 L3MBTL1 (0.35) MEN1MAPTKMT2AKDM4EPOLB
SCHEMBL12166327 0.85
SCHEMBL12166297 0.85 MEN1 (0.41) MEN1MAPTKMT2AKDM4ENPC1
SCHEMBL12166331 0.84 GP6 (0.35) MEN1MAPTKMT2AKDM4EL3MBTL1
SCHEMBL12166334 0.84 GP6 (0.35) MEN1MAPTKMT2AKDM4EL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11760734-B2 Materials for organic electroluminescent devices MERCK PATENT GMBH (DE) 2023-09-19 US disclosed
US-11760734-B2 Materials for organic electroluminescent devices MERCK PATENT GMBH (DE) 2023-09-19 US disclosed
US-20210221775-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2021-07-22 US disclosed
US-10981880-B2 Materials for organic electroluminescent devices MERCK PATENT GMBH (DE) 2021-04-20 US disclosed
US-20190169139-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2019-06-06 US disclosed
US-10233159-B2 Materials for organic electroluminescent devices MERCK PATENT GMBH (DE) 2019-03-19 US disclosed
US-20160096809-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2016-04-07 US disclosed
US-20160096809-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2016-04-07 US disclosed
US-9187456-B2 Materials for organic electroluminescent devices MERCK PATENT GMBH (DE) 2015-11-17 US disclosed
US-20120228554-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2012-09-13 US disclosed
US-20120228554-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2012-09-13 US disclosed
WO-2011060859-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2011-05-26 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10233159-B2 Materials for organic electroluminescent devices SLCO4C1, SLCO2B1, SLCO2A1 MEN1 665/4885MAPT 428/4885KMT2A 2454/4885
US-20190169139-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES SLCO4C1, SLCO2B1, SLCO2A1 MEN1 665/4885MAPT 428/4885KMT2A 2454/4885
US-20210221775-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES SLCO4C1, SLCO2B1, SLCO2A1 MEN1 665/4885MAPT 428/4885KMT2A 2454/4885
US-10981880-B2 Materials for organic electroluminescent devices SLCO4C1, SLCO2B1, SLCO2A1 MEN1 665/4885MAPT 428/4885KMT2A 2454/4885
US-20120228554-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES SLCO4C1, SLCO2B1, SLCO2A1 MEN1 665/4885MAPT 428/4885KMT2A 2454/4885
US-20160096809-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES SLCO4C1, SLCO2B1, SLCO2A1 MEN1 665/4885MAPT 428/4885KMT2A 2454/4885
US-11760734-B2 Materials for organic electroluminescent devices SLCO4C1, SLCO2B1, SLCO2A1 MEN1 665/4885MAPT 428/4885KMT2A 2454/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.