Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 4/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | TNNC1 | P63316 | 5/20 | 0.34 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.34 |
| ▸ | SGPL1 | O95470 | 1/20 | 0.34 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.34 |
| ▸ | GPR183 | P32249 | 1/20 | 0.34 |
| ▸ | CERS2 | Q96G23 | 1/20 | 0.34 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.34 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.34 |
| ▸ | ESR1 | P03372 | 2/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.33 |
| ▸ | TACR2 | P21452 | 2/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.33 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3555634 | 0.81 | PTGS2 (0.48) | PTGS2HTR2ACYP3A4TNNC1S1PR1 | |
| SCHEMBL2012315 | 0.81 | PTGS2 (0.48) | PTGS2HTR2ACYP3A4TNNC1S1PR1 | |
| SCHEMBL1323842 | 0.81 | PTGS2 (0.48) | PTGS2HTR2ACYP3A4TNNC1S1PR1 | |
| SCHEMBL196514 | 0.81 | PTGS2 (0.48) | PTGS2HTR2ACYP3A4TNNC1S1PR1 | |
| SCHEMBL14351415 | 0.79 | PTGS2 (0.39) | PTGS2HTR2ACYP3A4TNNC1S1PR1 | |
| SCHEMBL18666095 | 0.76 | PTGS2 (0.34) | PTGS2HTR2ACYP3A4ESR1ADRA2A | |
| SCHEMBL18665507 | 0.76 | PTGS2 (0.34) | PTGS2HTR2ACYP3A4ESR1ADRA2A | |
| SCHEMBL15458184 | 0.76 | PTGS2 (0.34) | PTGS2HTR2ACYP3A4ESR1ADRA2A | |
| SCHEMBL18665493 | 0.76 | PTGS2 (0.34) | PTGS2HTR2ACYP3A4ESR1ADRA2A | |
| SCHEMBL12170124 | 0.76 | PTGS2 (0.34) | PTGS2HTR2ACYP3A4ESR1ADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8735536-B2 | Naphthobisthiadiazole polymers for use in organic semiconductor devices | POLYERA CORPORATION (US) | 2014-05-27 | — | — | US | disclosed |
| US-8735536-B2 | Naphthobisthiadiazole polymers for use in organic semiconductor devices | POLYERA CORPORATION (US) | 2014-05-27 | — | — | US | disclosed |
| US-20120227812-A1 | NAPHTHOBISTHIADIAZOLE POLYMERS FOR USE IN ORGANIC SEMICONDUCTOR DEVICES | RAYNERGY TEK INC. (TW) | 2012-09-13 | — | — | US | disclosed |