Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 4/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | ESR1 | P03372 | 2/20 | 0.44 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.44 |
| ▸ | TACR2 | P21452 | 2/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | SHBG | P04278 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.44 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.44 |
| ▸ | HTR2C | P28335 | 1/20 | 0.44 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | TST | Q16762 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3555634 | 1.00 | PTGS2 (0.48) | PTGS2CYP3A4ESR1ADRA2AADORA3 | |
| SCHEMBL1323842 | 1.00 | PTGS2 (0.48) | PTGS2CYP3A4ESR1ADRA2AADORA3 | |
| SCHEMBL196514 | 1.00 | PTGS2 (0.48) | PTGS2CYP3A4ESR1ADRA2AADORA3 | |
| SCHEMBL1492468 | 0.91 | PTGS2 (0.42) | PTGS2CYP3A4ESR1ADRA2AADORA3 | |
| SCHEMBL14881251 | 0.91 | PTGS2 (0.42) | PTGS2CYP3A4ESR1ADRA2AADORA3 | |
| SCHEMBL10046697 | 0.91 | PTGS2 (0.42) | PTGS2CYP3A4ESR1ADRA2AADORA3 | |
| SCHEMBL17528639 | 0.89 | PTGS2 (0.41) | PTGS2CYP3A4ESR1ADRA2AADORA3 | |
| SCHEMBL17528653 | 0.89 | HSD17B10 (0.44) | PTGS2CYP3A4ESR1ADRA2AADORA3 | |
| SCHEMBL18044490 | 0.87 | KDM4E (0.39) | PTGS2CYP3A4ESR1ADRA2AADORA3 | |
| SCHEMBL27911329 | 0.87 | KDM4E (0.39) | PTGS2CYP3A4ESR1ADRA2AADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170044309-A1 | PREPARATION OF HIGH MOLECULAR WEIGHT POLYMERS BY DIRECT ARYLATION AND HETEROARYLATION | UNIVERSITE LAVAL (CA) | 2017-02-16 | — | — | US | disclosed |
| US-20170044309-A1 | PREPARATION OF HIGH MOLECULAR WEIGHT POLYMERS BY DIRECT ARYLATION AND HETEROARYLATION | UNIVERSITE LAVAL (CA) | 2017-02-16 | — | — | US | disclosed |
| US-9505876-B2 | Preparation of high molecular weight polymers by direct arylation and heteroarylation | UNIVERSITE LAVAL (CA) | 2016-11-29 | — | — | US | disclosed |
| US-20140371409-A1 | PREPARATION OF HIGH MOLECULAR WEIGHT POLYMERS BY DIRECT ARYLATION AND HETEROARYLATION | UNIVERSITE LAVAL (CA) | 2014-12-18 | — | — | US | disclosed |
| US-7964650-B2 | Carbonyl-functionalized thiophene compounds and related device structures | NORTHWESTERN UNIVERSITY (US) | 2011-06-21 | — | — | US | disclosed |
| US-20090267061-A1 | Carbonyl-Functionalized Thiophene Compounds and Related Device Structures | POLYERA CORPORATION | 2009-10-29 | — | — | US | disclosed |
| US-7528176-B2 | organic field effect transistor device comprising semiconductor component (comprises a composition of thiophene-carbonyl compounds and polymer); enhanced solubility in a solvent and thermal stablity; promote electron and hole mobilities; in thermal analysis, molecular spectroscopy, electrochemistry | NORTHWESTERN UNIVERSITY (US) | 2009-05-05 | — | — | US | disclosed |
| EP-1831205-A1 | CARBONYL-FUNCTIONALIZED THIOPHENE COMPOUNDS AND RELATED DEVICE STRUCTURES | Northwestern University (US) | 2007-09-12 | — | — | EP | disclosed |
| WO-2007050049-A1 | CARBONYL-FUNCTIONALIZED THIOPHENE COMPOUNDS AND RELATED DEVICE STRUCTURES | NORTHWESTERN UNIVERSITY (US) | 2007-05-03 | — | — | WO | disclosed |
| US-20060186401-A1 | Carbonyl-functionalized thiophene compounds and related device structures | POLYERA CORPORATION | 2006-08-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090267061-A1 | Carbonyl-Functionalized Thiophene Compounds and Related Device Structures | TEC, OR10J3, TRPA1 | PTGS2 1843/4885CYP3A4 1653/4885ESR1 1096/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.