Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.38 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29001469 | 0.94 | ALDH1A1 (0.39) | KMT2AGPR84FFAR1ALDH1A1LMNA | |
| SCHEMBL12190162 | 0.85 | CYP1A2 (0.52) | KMT2AALDH1A1LMNAHSD17B10POLB | |
| SCHEMBL28343057 | 0.83 | KMT2A (0.53) | KMT2AALDH1A1LMNAHSD17B10POLB | |
| SCHEMBL28343058 | 0.83 | FFAR1 (0.55) | KMT2AGPR84FFAR1ALDH1A1HSD17B10 | |
| SCHEMBL15154065 | 0.83 | KMT2A (0.53) | KMT2AALDH1A1LMNAHSD17B10POLB | |
| SCHEMBL4249572 | 0.83 | FFAR1 (0.55) | KMT2AGPR84FFAR1ALDH1A1HSD17B10 | |
| SCHEMBL3019389 | 0.82 | GPR84 (0.57) | GPR84FFAR1FFAR4 | |
| SCHEMBL22631834 | 0.81 | GPR84 (0.49) | GPR84FFAR1FFAR4 | |
| SCHEMBL509990 | 0.80 | GPR84 (0.61) | GPR84FFAR1FFAR4 | |
| SCHEMBL9773213 | 0.80 | GPR84 (0.61) | GPR84FFAR1FFAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120231512-A1 | PREPARATION OF ALPHA-KETOPIMELIC ACID | DSM IP ASSETS B.V. (NL) | 2012-09-13 | — | — | US | disclosed |