Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | GAA | P10253 | 3/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 3/20 | 0.32 |
| ▸ | CA2 | P00918 | 3/20 | 0.32 |
| ▸ | CA9 | Q16790 | 3/20 | 0.32 |
| ▸ | CA1 | P00915 | 2/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
| ▸ | NSD2 | O96028 | 1/20 | 0.31 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.31 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11968681 | 0.86 | ALDH1A1 (0.31) | ALDH1A1GAAHSD17B10MAPTKDM4E | |
| SCHEMBL7188467 | 0.78 | GAA (0.47) | ALDH1A1GAAHSD17B10MAPTKDM4E | |
| SCHEMBL19511694 | 0.76 | PTK2 (0.30) | — | |
| SCHEMBL10206836 | 0.74 | TDP1 (0.43) | ALDH1A1GAAHSD17B10MAPTKDM4E | |
| SCHEMBL10208077 | 0.73 | HSD17B10 (0.50) | ALDH1A1GAAHSD17B10MAPTKDM4E | |
| SCHEMBL24265884 | 0.72 | KDM4E (0.42) | ALDH1A1GAAHSD17B10MAPTKDM4E | |
| SCHEMBL18822076 | 0.71 | ALDH1A1 (0.32) | ALDH1A1HSD17B10 | |
| SCHEMBL13806490 | 0.70 | ALDH1A1 (0.36) | ALDH1A1GAAHSD17B10MAPTKDM4E | |
| SCHEMBL17366351 | 0.69 | ALDH1A1 (0.36) | ALDH1A1HSD17B10MAPTLMNATP53 | |
| SCHEMBL13325401 | 0.69 | BACE1 (0.50) | ALDH1A1HSD17B10LMNACA12CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110269243-A1 | SYSTEMS AND METHODS RELATED TO OPTICAL NANOSENSORS COMPRISING PHOTOLUMINESCENT NANOSTRUCTURES | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2011-11-03 | — | — | US | disclosed |