Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 8/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 5/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | HTT | P42858 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | RECQL | P46063 | 2/20 | 0.42 |
| ▸ | USP2 | O75604 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10208077 | 0.82 | HSD17B10 (0.50) | GAAMAPTCA12CA1CA2 | |
| SCHEMBL12174816 | 0.78 | ALDH1A1 (0.36) | GAAMAPTCA12CA1CA2 | |
| SCHEMBL3316934 | 0.78 | PTGS2 (0.48) | GAAMAPTCA12CA1CA2 | |
| SCHEMBL10206836 | 0.78 | TDP1 (0.43) | GAAMAPTALDH1A1HSD17B10ALOX15 | |
| SCHEMBL10942449 | 0.77 | ALDH1A1 (0.46) | GAAMAPTCA12CA1CA2 | |
| SCHEMBL10889596 | 0.77 | GAA (0.42) | GAAMAPTCA12CA1CA2 | |
| SCHEMBL12228262 | 0.74 | MAPT (0.40) | MAPTCA1CA2ALDH1A1HSD17B10 | |
| SCHEMBL639211 | 0.73 | RAB9A (0.52) | GAAMAPTALDH1A1HSD17B10ALOX15 | |
| SCHEMBL11213671 | 0.73 | PTGS1 (0.53) | MAPTCA1CA2ALDH1A1HSD17B10 | |
| SCHEMBL18403872 | 0.73 | ALOX15 (0.50) | CA12CA1CA2CA9ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105585874-B | A kind of active gray dyes and preparation method thereof | 浙江劲光实业股份有限公司 | 2017-07-04 | — | — | CN | claimed |
| CN-107935893-A | A kind of production line for producing a variety of dyestuff intermediates | 青岛海湾集团有限公司 | 2018-04-20 | — | — | CN | disclosed |
| CN-104146911-B | Oxidising dyeing composition containing natural materials | 株式会社太平洋 | 2018-01-23 | — | — | CN | disclosed |
| CN-107531625-A | Aromatic diamine and its intermediate and their manufacture method | 精化株式会社 | 2018-01-02 | — | — | CN | disclosed |
| CN-107501099-A | The adjusting control agent of ATP combination cassette transporters | 沃泰克斯药物股份有限公司 | 2017-12-22 | — | — | CN | disclosed |
| CN-107253914-A | The method that the nitrophenol of 2 amino 4 is prepared using Disperse Blue 2BLN byproduct | 青岛海湾集团有限公司 | 2017-10-17 | — | — | CN | disclosed |
| WO-2017159484-A1 | 2,4-DIAMINOPHENOL DERIVATIVE, AND AGENT FOR INHIBITING AGGREGATION OF TAU AND/OR AMYLOID β | 学校法人同志社 | 2017-09-21 | — | — | WO | disclosed |
| CN-104788328-B | The adjusting control agent of ATP combination cassette transporters | 沃泰克斯药物股份有限公司 | 2017-09-12 | — | — | CN | disclosed |
| CN-105585874-B | A kind of active gray dyes and preparation method thereof | 浙江劲光实业股份有限公司 | 2017-07-04 | — | — | CN | disclosed |
| CN-106674145-A | Preparation method of 2-aryl benzoxazole and 2-aryl benzothiazole compounds | 复旦大学 | 2017-05-17 | — | — | CN | disclosed |
| US-20110269243-A1 | SYSTEMS AND METHODS RELATED TO OPTICAL NANOSENSORS COMPRISING PHOTOLUMINESCENT NANOSTRUCTURES | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2011-11-03 | — | — | US | disclosed |
| CN-101935301-A | Modulators of ATP-binding cassette transporters | VERTEX PHARMA | 2011-01-05 | — | — | CN | disclosed |
| CN-101891680-A | The adjusting control agent of ATP- combination cassette transporters | VERTEX PHARMA | 2010-11-24 | — | — | CN | disclosed |
| WO-2010111483-A1 | INHIBITORS OF HEPATITIS C VIRUS REPLICATION | MERCK SHARP & DOHME CORP. (US) | 2010-09-30 | — | — | WO | disclosed |
| WO-2009031011-A2 | XINAFOATE SALT OF N4-(2, 2-DIFLUORO-4H-BENZ0 [1,4] 0XAZIN-3-ONE) -6-YL] -5-FLUORO-N2- [3- (METHYLAMINOCAR BONYLMETHYLENEOXY) PHENYL] 2, 4-PYRIMIDINEDIAMINE | PFIZER LIMITED (GB) | 2009-03-12 | — | — | WO | disclosed |
| WO-2009010533-A1 | AROMATIC HYDROGENATED POLYMERS CONTAINING FLUORINE | SOLVAY SOLEXIS S.P.A. (IT) | 2009-01-22 | — | — | WO | disclosed |
| CN-1204211-C | Water-based ink-jet dye | UNIV DALIAN TECH (CN) | 2005-06-01 | — | — | CN | disclosed |
| CN-1448449-A | Water-based ink-jet dye | SHANGHAI POLYTECHNIC UNIVERSIT (CN) | 2003-10-15 | — | — | CN | disclosed |
| EP-1304924-A2 | COMPOSITIONS FOR REPELLING CRAWLING INSECTS | Bayer Aktiengesellschaft (DE) | 2003-05-02 | — | — | EP | disclosed |
| WO-2002005646-A2 | COMPOSITIONS FOR REPELLING CRAWLING INSECTS | S.C. JOHNSON & SON, INC. (US) (US) | 2002-01-24 | — | — | WO | disclosed |