Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.56 |
| ▸ | MAPT | P10636 | 4/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.53 |
| ▸ | MGAM | O43451 | 1/20 | 0.53 |
| ▸ | CA12 | O43570 | 1/20 | 0.53 |
| ▸ | CA1 | P00915 | 1/20 | 0.53 |
| ▸ | CA2 | P00918 | 1/20 | 0.53 |
| ▸ | CA9 | Q16790 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | FAAH | O00519 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12177692 | 0.94 | ALDH1A1 (0.52) | ALDH1A1MAPTNPSR1TDP1L3MBTL1 | |
| SCHEMBL12177693 | 0.94 | TDP1 (0.50) | ALDH1A1MAPTNPSR1TDP1L3MBTL1 | |
| SCHEMBL12177544 | 0.88 | ALDH1A1 (0.58) | ALDH1A1MAPTNPSR1TDP1L3MBTL1 | |
| SCHEMBL12177516 | 0.85 | ALDH1A1 (0.57) | ALDH1A1MAPTNPSR1TDP1L3MBTL1 | |
| SCHEMBL12177373 | 0.85 | MGAM (0.61) | ALDH1A1MAPTNPSR1TDP1L3MBTL1 | |
| SCHEMBL12177530 | 0.85 | ALDH1A1 (0.59) | ALDH1A1MAPTNPSR1TDP1L3MBTL1 | |
| SCHEMBL12177694 | 0.83 | CISD1 (0.47) | TDP1CYP3A4CYP2C9CYP1A2CYP2C19 | |
| SCHEMBL12177167 | 0.83 | TDP1 (0.60) | ALDH1A1MAPTTDP1L3MBTL1POLB | |
| SCHEMBL12177149 | 0.81 | AURKA (0.53) | ALDH1A1MAPTNPSR1TDP1L3MBTL1 | |
| SCHEMBL2594707 | 0.81 | CA9 (0.54) | ALDH1A1MAPTTDP1POLBGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011135303-A2 | UBIQUITINATION MODULATORS | ITI SCOTLAND LIMITED (GB) | 2011-11-03 | — | — | WO | disclosed |