Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 12/20 | 0.58 |
| ▸ | MAPT | P10636 | 7/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 5/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | GAA | P10253 | 1/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.57 |
| ▸ | MGAM | O43451 | 1/20 | 0.55 |
| ▸ | CA12 | O43570 | 1/20 | 0.55 |
| ▸ | CA1 | P00915 | 1/20 | 0.55 |
| ▸ | CA2 | P00918 | 1/20 | 0.55 |
| ▸ | CA9 | Q16790 | 1/20 | 0.55 |
| ▸ | FAAH | O00519 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12177528 | 0.93 | ALDH1A1 (0.48) | ALDH1A1MAPTNPSR1TDP1L3MBTL1 | |
| SCHEMBL12177692 | 0.90 | ALDH1A1 (0.52) | ALDH1A1MAPTNPSR1TDP1L3MBTL1 | |
| SCHEMBL12177530 | 0.88 | ALDH1A1 (0.59) | ALDH1A1MAPTNPSR1TDP1L3MBTL1 | |
| SCHEMBL12177263 | 0.88 | ALDH1A1 (0.56) | ALDH1A1MAPTNPSR1TDP1L3MBTL1 | |
| SCHEMBL12177707 | 0.88 | MGAM (0.53) | ALDH1A1MAPTNPSR1TDP1L3MBTL1 | |
| SCHEMBL12177425 | 0.87 | LMNA (0.56) | ALDH1A1MAPTTDP1L3MBTL1POLB | |
| SCHEMBL12177149 | 0.87 | AURKA (0.53) | ALDH1A1MAPTNPSR1TDP1L3MBTL1 | |
| SCHEMBL12177724 | 0.82 | ALDH1A1 (0.59) | ALDH1A1MAPTNPSR1TDP1L3MBTL1 | |
| SCHEMBL12177693 | 0.82 | TDP1 (0.50) | ALDH1A1MAPTNPSR1TDP1L3MBTL1 | |
| SCHEMBL12177727 | 0.82 | ALDH1A1 (0.59) | ALDH1A1MAPTNPSR1TDP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011135303-A2 | UBIQUITINATION MODULATORS | ITI SCOTLAND LIMITED (GB) | 2011-11-03 | — | — | WO | disclosed |