Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | DVL1 | O14640 | 1/20 | 0.40 |
| ▸ | MITF | O75030 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | KDR | P35968 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.38 |
| ▸ | PTPN12 | Q05209 | 1/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12177470 | 0.90 | KMT2A (0.42) | KMT2AMEN1DVL1MITFPPARG | |
| SCHEMBL12177348 | 0.90 | KMT2A (0.42) | KMT2AMEN1MAPK1CA9MITF | |
| SCHEMBL12177133 | 0.88 | PPARG (0.46) | KMT2AMEN1CA9DVL1MITF | |
| SCHEMBL12177352 | 0.86 | CISD1 (0.47) | KMT2AMEN1MAPK1MAPTCA9 | |
| SCHEMBL12177127 | 0.86 | PTPN1 (0.45) | KMT2AMEN1POLBPTPN7PTPN12 | |
| SCHEMBL12177380 | 0.84 | KMT2A (0.53) | KMT2AMEN1MAPTALDH1A1POLB | |
| SCHEMBL12177367 | 0.83 | MAPK1 (0.49) | MAPK1MAPTCA9PPARGALDH1A1 | |
| SCHEMBL12177406 | 0.81 | PPARG (0.54) | KMT2AMEN1MAPK1MAPTCA9 | |
| SCHEMBL12177361 | 0.80 | ENPP2 (0.46) | KMT2AMEN1MAPK1MAPTALDH1A1 | |
| SCHEMBL12177764 | 0.80 | PPARG (0.44) | KMT2AMEN1DVL1PPARGALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011135303-A2 | UBIQUITINATION MODULATORS | ITI SCOTLAND LIMITED (GB) | 2011-11-03 | — | — | WO | disclosed |