Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | CA9 | Q16790 | 1/20 | 0.48 |
| ▸ | PPARG | P37231 | 5/20 | 0.48 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.47 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.47 |
| ▸ | ACP1 | P24666 | 1/20 | 0.47 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.47 |
| ▸ | PIM1 | P11309 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12177406 | 0.96 | PPARG (0.54) | MAPK1KDM4EALDH1A1LMNAMAPT | |
| SCHEMBL12177366 | 0.95 | ENPP2 (0.54) | ALDH1A1PPARGPTPN1ENPP2 | |
| SCHEMBL12177568 | 0.86 | MAPK1 (0.66) | MAPK1KDM4EALDH1A1LMNAMAPT | |
| SCHEMBL12177303 | 0.85 | ENPP2 (0.55) | PTPN1ACP1ENPP2 | |
| SCHEMBL12177484 | 0.84 | PPARG (0.55) | ALDH1A1PPARGPTPN1ACP1ENPP2 | |
| SCHEMBL12177277 | 0.83 | KMT2A (0.43) | MAPK1ALDH1A1MAPTPKMCA9 | |
| SCHEMBL12177450 | 0.83 | MAPK1 (0.41) | MAPK1KDM4EALDH1A1LMNAMAPT | |
| SCHEMBL12177353 | 0.82 | PIM1 (0.59) | MAPK1KDM4EALDH1A1LMNAMAPT | |
| SCHEMBL12177155 | 0.82 | PPARG (0.63) | ALDH1A1PPARGPTPN1ACP1ENPP2 | |
| SCHEMBL12177400 | 0.82 | PPARG (0.66) | MAPK1KDM4EALDH1A1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011135303-A2 | UBIQUITINATION MODULATORS | ITI SCOTLAND LIMITED (GB) | 2011-11-03 | — | — | WO | disclosed |