Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.61 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.53 |
| ▸ | ITGAV | P06756 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 3/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | RECQL | P46063 | 1/20 | 0.51 |
| ▸ | PTPN2 | P17706 | 3/20 | 0.50 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.50 |
| ▸ | ACP1 | P24666 | 3/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12177483 | 0.91 | TDP1 (0.51) | ALDH1A1ITGB3ITGAVPOLBMAPT | |
| SCHEMBL12177516 | 0.91 | ALDH1A1 (0.57) | ALDH1A1ITGB3ITGAVPOLBMAPT | |
| SCHEMBL12177442 | 0.90 | ALDH1A1 (0.62) | ALDH1A1ITGB3ITGAVPOLBMAPT | |
| SCHEMBL12177522 | 0.88 | ALDH1A1 (0.50) | ALDH1A1ITGB3ITGAVPOLBMAPT | |
| SCHEMBL12177501 | 0.83 | PTPN2 (0.61) | ALDH1A1ITGB3ITGAVPOLBMAPT | |
| SCHEMBL12177731 | 0.83 | PTPN2 (0.61) | ALDH1A1ITGB3ITGAVPOLBMAPT | |
| SCHEMBL12177123 | 0.82 | ALDH1A1 (0.64) | ALDH1A1ITGB3ITGAVPOLBMAPT | |
| SCHEMBL12177542 | 0.82 | ALDH1A1 (0.64) | ALDH1A1ITGB3ITGAVPOLBMAPT | |
| SCHEMBL12177391 | 0.80 | PTPN2 (0.57) | ALDH1A1ITGB3ITGAVPOLBMAPT | |
| SCHEMBL12177373 | 0.79 | MGAM (0.61) | ALDH1A1POLBMAPTTDP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011135303-A2 | UBIQUITINATION MODULATORS | ITI SCOTLAND LIMITED (GB) | 2011-11-03 | — | — | WO | disclosed |