Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | MGAM | O43451 | 3/20 | 0.48 |
| ▸ | CA12 | O43570 | 3/20 | 0.48 |
| ▸ | CA1 | P00915 | 3/20 | 0.48 |
| ▸ | CA2 | P00918 | 3/20 | 0.48 |
| ▸ | CA9 | Q16790 | 3/20 | 0.48 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.47 |
| ▸ | ITGAV | P06756 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | AURKA | O14965 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | PTP4A3 | O75365 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12177516 | 0.93 | ALDH1A1 (0.57) | ALDH1A1NPSR1GAATDP1POLB | |
| SCHEMBL12177483 | 0.91 | TDP1 (0.51) | ALDH1A1NPSR1GAATDP1POLB | |
| SCHEMBL12177449 | 0.88 | ALDH1A1 (0.61) | ALDH1A1NPSR1GAATDP1POLB | |
| SCHEMBL12177126 | 0.87 | MGAM (0.54) | ALDH1A1NPSR1GAATDP1POLB | |
| SCHEMBL12177404 | 0.83 | AURKA (0.55) | ALDH1A1GAATDP1POLBMAPT | |
| SCHEMBL12177547 | 0.83 | PSMB8 (0.56) | ALDH1A1NPSR1GAATDP1POLB | |
| SCHEMBL12177552 | 0.82 | MGAM (0.57) | ALDH1A1NPSR1GAATDP1POLB | |
| SCHEMBL12177732 | 0.82 | MGAM (0.57) | ALDH1A1NPSR1GAATDP1POLB | |
| SCHEMBL12177373 | 0.81 | MGAM (0.61) | ALDH1A1NPSR1GAATDP1POLB | |
| SCHEMBL12177288 | 0.80 | TDP1 (0.55) | ALDH1A1NPSR1GAATDP1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011135303-A2 | UBIQUITINATION MODULATORS | ITI SCOTLAND LIMITED (GB) | 2011-11-03 | — | — | WO | disclosed |