Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.48 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.34 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.34 |
| ▸ | FEN1 | P39748 | 1/20 | 0.34 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | GCK | P35557 | 3/20 | 0.34 |
| ▸ | NPY2R | P49146 | 5/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | CA12 | O43570 | 2/20 | 0.33 |
| ▸ | CA1 | P00915 | 2/20 | 0.33 |
| ▸ | CA9 | Q16790 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9923147 | 0.93 | P2RY12 (0.54) | P2RY12ERCC1FEN1ERCC4KDM4E | |
| SCHEMBL14113677 | 0.93 | P2RY12 (0.44) | P2RY12BRD4CREBBPERCC1FEN1 | |
| SCHEMBL12177237 | 0.91 | P2RY12 (0.49) | P2RY12BRD4CREBBPERCC1FEN1 | |
| SCHEMBL14113683 | 0.89 | P2RY12 (0.51) | P2RY12BRD4CREBBPERCC1FEN1 | |
| SCHEMBL9922505 | 0.86 | P2RY12 (0.58) | P2RY12ERCC1FEN1ERCC4GCK | |
| SCHEMBL13638702 | 0.84 | P2RY12 (0.38) | P2RY12ERCC1FEN1ERCC4KDM4E | |
| SCHEMBL9922877 | 0.84 | P2RY12 (0.58) | P2RY12ERCC1FEN1ERCC4KDM4E | |
| SCHEMBL9922645 | 0.83 | P2RY12 (0.64) | P2RY12GCKMAPTTP53KMT2A | |
| SCHEMBL9923149 | 0.83 | P2RY12 (0.59) | P2RY12ERCC1FEN1ERCC4KDM4E | |
| SCHEMBL9922879 | 0.82 | P2RY12 (0.56) | P2RY12ERCC1FEN1ERCC4KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8067428-B2 | Platelet ADP receptor inhibitors | PORTOLA PHARMACEUTICALS, INC. (US) | 2011-11-29 | — | — | US | disclosed |
| US-20100234350-A1 | PLATELET ADP RECEPTOR INHIBITORS | PORTOLA PHARMACEUTICALS, INC. (US) | 2010-09-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100234350-A1 | PLATELET ADP RECEPTOR INHIBITORS | TBXA2R, GP6, P2RY6 | P2RY12 19/4885BRD4 3071/4885CREBBP 3070/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.