Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA9 | Q16790 | 6/20 | 0.69 |
| ▸ | MGAM | O43451 | 5/20 | 0.69 |
| ▸ | CA12 | O43570 | 5/20 | 0.69 |
| ▸ | CA1 | P00915 | 5/20 | 0.69 |
| ▸ | CA2 | P00918 | 5/20 | 0.69 |
| ▸ | AURKA | O14965 | 7/20 | 0.64 |
| ▸ | LMNA | P02545 | 1/20 | 0.64 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.64 |
| ▸ | GAA | P10253 | 1/20 | 0.64 |
| ▸ | CISD1 | Q9NZ45 | 2/20 | 0.53 |
| ▸ | MAOB | P27338 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12177712 | 0.92 | AURKA (0.75) | CA9MGAMCA12CA1CA2 | |
| SCHEMBL12177571 | 0.91 | CA9 (0.69) | CA9MGAMCA12CA1CA2 | |
| SCHEMBL12177685 | 0.89 | AURKA (0.65) | CA9MGAMCA12CA1CA2 | |
| SCHEMBL12177509 | 0.89 | CA9 (0.61) | CA9MGAMCA12CA1CA2 | |
| SCHEMBL12177682 | 0.86 | CA9 (0.70) | CA9MGAMCA12CA1CA2 | |
| SCHEMBL12177166 | 0.86 | AURKA (0.70) | CA9MGAMCA12CA1CA2 | |
| SCHEMBL12177126 | 0.85 | MGAM (0.54) | CA9MGAMCA12CA1CA2 | |
| SCHEMBL12177783 | 0.85 | MGAM (0.57) | CA9MGAMCA12CA1CA2 | |
| SCHEMBL2594707 | 0.83 | CA9 (0.54) | CA9MGAMCA12CA1CA2 | |
| SCHEMBL12177404 | 0.83 | AURKA (0.55) | CA9MGAMCA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011135303-A2 | UBIQUITINATION MODULATORS | ITI SCOTLAND LIMITED (GB) | 2011-11-03 | — | — | WO | disclosed |