Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AURKA | O14965 | 4/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.55 |
| ▸ | CA9 | Q16790 | 3/20 | 0.52 |
| ▸ | MGAM | O43451 | 2/20 | 0.52 |
| ▸ | CA12 | O43570 | 2/20 | 0.52 |
| ▸ | CA1 | P00915 | 2/20 | 0.52 |
| ▸ | CA2 | P00918 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.50 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.45 |
| ▸ | ITGAV | P06756 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12177126 | 0.96 | MGAM (0.54) | AURKALMNATDP1CA9MGAM | |
| SCHEMBL12177776 | 0.90 | TDP1 (0.56) | AURKALMNATDP1CA9MGAM | |
| SCHEMBL12177123 | 0.89 | ALDH1A1 (0.64) | AURKALMNATDP1CA9MGAM | |
| SCHEMBL12177542 | 0.89 | ALDH1A1 (0.64) | AURKALMNATDP1CA9MGAM | |
| SCHEMBL12177138 | 0.86 | ALDH1A1 (0.53) | AURKALMNATDP1CA9MGAM | |
| SCHEMBL12177714 | 0.83 | CA9 (0.69) | AURKALMNATDP1CA9MGAM | |
| SCHEMBL12177522 | 0.83 | ALDH1A1 (0.50) | AURKALMNATDP1CA9MGAM | |
| SCHEMBL12177697 | 0.83 | LMNA (0.55) | AURKALMNATDP1CA9MGAM | |
| SCHEMBL12177483 | 0.81 | TDP1 (0.51) | AURKALMNATDP1CA9MGAM | |
| SCHEMBL12177509 | 0.79 | CA9 (0.61) | AURKALMNATDP1CA9MGAM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011135303-A2 | UBIQUITINATION MODULATORS | ITI SCOTLAND LIMITED (GB) | 2011-11-03 | — | — | WO | disclosed |