Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGAM | O43451 | 2/20 | 0.54 |
| ▸ | CA12 | O43570 | 2/20 | 0.54 |
| ▸ | CA1 | P00915 | 2/20 | 0.54 |
| ▸ | CA2 | P00918 | 2/20 | 0.54 |
| ▸ | CA9 | Q16790 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | AURKA | O14965 | 8/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.46 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12177404 | 0.96 | AURKA (0.55) | MGAMCA12CA1CA2CA9 | |
| SCHEMBL12177138 | 0.90 | ALDH1A1 (0.53) | MGAMCA12CA1CA2CA9 | |
| SCHEMBL12177123 | 0.89 | ALDH1A1 (0.64) | MGAMCA12CA1CA2CA9 | |
| SCHEMBL12177542 | 0.89 | ALDH1A1 (0.64) | MGAMCA12CA1CA2CA9 | |
| SCHEMBL12177522 | 0.87 | ALDH1A1 (0.50) | MGAMCA12CA1CA2CA9 | |
| SCHEMBL12177776 | 0.86 | TDP1 (0.56) | MGAMCA12CA1CA2CA9 | |
| SCHEMBL12177714 | 0.85 | CA9 (0.69) | MGAMCA12CA1CA2CA9 | |
| SCHEMBL2594706 | 0.83 | CA9 (0.54) | MGAMCA12CA1CA2CA9 | |
| SCHEMBL2594705 | 0.83 | CA9 (0.54) | MGAMCA12CA1CA2CA9 | |
| SCHEMBL2594707 | 0.83 | CA9 (0.54) | MGAMCA12CA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011135303-A2 | UBIQUITINATION MODULATORS | ITI SCOTLAND LIMITED (GB) | 2011-11-03 | — | — | WO | disclosed |