Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.51 |
| ▸ | TP53 | P04637 | 2/20 | 0.51 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 7/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 6/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12651849 | 0.81 | HTT (0.61) | MAPTTP53TRPV1POLBHPGD | |
| SCHEMBL17660226 | 0.81 | HPGD (0.70) | MAPTTP53TRPV1POLBHPGD | |
| SCHEMBL12069179 | 0.76 | NPC1 (0.55) | MAPTHTTLMNAKDM4ERAB9A | |
| SCHEMBL12068682 | 0.75 | RAB9A (0.68) | MAPTLMNAKDM4ERAB9AL3MBTL1 | |
| SCHEMBL12067847 | 0.74 | NPC1 (0.50) | MAPTPOLBHPGDHTTLMNA | |
| SCHEMBL15652533 | 0.74 | MAPT (0.55) | MAPTTP53TRPV1POLBHTT | |
| SCHEMBL12067338 | 0.72 | RAB9A (0.54) | MAPTHPGDHTTLMNAKDM4E | |
| SCHEMBL24119315 | 0.71 | HDAC1 (0.71) | MAPTTP53RAB9ANPC1 | |
| SCHEMBL28574207 | 0.71 | POLB (0.68) | MAPTTP53POLBHPGDRAB9A | |
| SCHEMBL11416317 | 0.70 | MAOA (0.56) | MAPTTP53POLBLMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011146483-A1 | DRUG DELIVERY DEVICES FOR DELIVERY OF OCULAR THERAPEUTIC AGENTS | AERIE PHARMACEUTICALS, INC. (US) | 2011-11-24 | — | — | WO | disclosed |