SCHEMBL12182004

SCHEMBL12182004

O=c1c2cc(-c3ccc(-c4ccccc4)cc3)ccc2oc2ccc(-c3ccc(-c4ccccc4)cc3)cc12

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PLA2G2A P14555 3/20 0.61
PLA2G4A P47712 3/20 0.61
PTPN1 P18031 2/20 0.57
PTPN2 P17706 1/20 0.57
TBK1 Q9UHD2 1/20 0.56
CASP3 P42574 1/20 0.55
SENP7 Q9BQF6 1/20 0.55
SENP6 Q9GZR1 1/20 0.55
MAOA P21397 3/20 0.54
MAPT P10636 2/20 0.54
SMN1; SMN2 Q16637 2/20 0.54
KDM4E B2RXH2 1/20 0.54
ALDH1A1 P00352 1/20 0.54
GLA P06280 1/20 0.54
CYP3A4 P08684 1/20 0.54
HPGD P15428 1/20 0.54
PGAM1 P18669 1/20 0.54
CASP1 P29466 1/20 0.54
CASP7 P55210 1/20 0.54
HSD17B10 Q99714 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12182006 1.00 PLA2G2A (0.61) PLA2G2APLA2G4APTPN1PTPN2TBK1
SCHEMBL4572512 1.00 PLA2G2A (0.61) PLA2G2APLA2G4APTPN1PTPN2TBK1
SCHEMBL12181772 0.96 PLA2G2A (0.57) PLA2G2APLA2G4APTPN1PTPN2TBK1
SCHEMBL10055304 0.96 PLA2G2A (0.57) PLA2G2APLA2G4APTPN1PTPN2TBK1
SCHEMBL12181751 0.96 PLA2G2A (0.57) PLA2G2APLA2G4APTPN1PTPN2TBK1
SCHEMBL4572439 0.96 PLA2G2A (0.57) PLA2G2APLA2G4APTPN1PTPN2TBK1
SCHEMBL4572473 0.96 PLA2G2A (0.57) PLA2G2APLA2G4APTPN1PTPN2TBK1
SCHEMBL12181747 0.96 PLA2G2A (0.57) PLA2G2APLA2G4APTPN1PTPN2TBK1
SCHEMBL6897957 0.94 MAOA (0.64) PLA2G2APLA2G4APTPN1PTPN2TBK1
SCHEMBL12181788 0.91 PLA2G2A (0.60) PLA2G2APLA2G4APTPN1PTPN2TBK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9269911-B2 Organic light-emitting device CANON KABUSHIKI KAISHA (JP) 2016-02-23 US disclosed
US-9269911-B2 Organic light-emitting device CANON KABUSHIKI KAISHA (JP) 2016-02-23 US disclosed
US-20130037791-A1 ORGANIC LIGHT-EMITTING DEVICE CANON KABUSHIKI KAISHA (JP) 2013-02-14 US disclosed
US-20130037791-A1 ORGANIC LIGHT-EMITTING DEVICE CANON KABUSHIKI KAISHA (JP) 2013-02-14 US disclosed
WO-2011136156-A1 ORGANIC LIGHT-EMITTING DEVICE CANON KABUSHIKI KAISHA (JP) 2011-11-03 WO disclosed