Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.49 |
| ▸ | NPC1 | O15118 | 4/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | CASP3 | P42574 | 2/20 | 0.49 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.49 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.49 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | BLM | P54132 | 1/20 | 0.49 |
| ▸ | PLEC | Q15149 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11614936 | 0.88 | RAB9A (0.69) | RAB9AALDH1A1KDM4ESMN1; SMN2NPC1 | |
| SCHEMBL23223734 | 0.88 | RAB9A (0.69) | RAB9AALDH1A1KDM4ESMN1; SMN2NPC1 | |
| SCHEMBL865349 | 0.81 | RAB9A (0.71) | RAB9AALDH1A1KDM4ESMN1; SMN2MAPT | |
| SCHEMBL8589028 | 0.81 | RAB9A (0.61) | RAB9AALDH1A1KDM4ESMN1; SMN2NPC1 | |
| SCHEMBL4054280 | 0.79 | SMN1; SMN2 (0.75) | RAB9AALDH1A1KDM4ESMN1; SMN2NPC1 | |
| SCHEMBL8621941 | 0.79 | RAB9A (0.59) | RAB9AALDH1A1KDM4ESMN1; SMN2NPC1 | |
| SCHEMBL1299394 | 0.79 | RAB9A (0.59) | RAB9AALDH1A1KDM4ESMN1; SMN2NPC1 | |
| SCHEMBL865744 | 0.79 | MAOB (0.67) | RAB9AALDH1A1KDM4ESMN1; SMN2NPC1 | |
| SCHEMBL13462927 | 0.79 | SMN1; SMN2 (0.75) | RAB9AALDH1A1KDM4ESMN1; SMN2NPC1 | |
| SCHEMBL864643 | 0.79 | RAB9A (0.69) | RAB9AALDH1A1SMN1; SMN2NPC1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011143772-A1 | INHIBITORS OF HIV REPLICATION | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2011-11-24 | — | — | WO | disclosed |