Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | MAOA | P21397 | 4/20 | 0.46 |
| ▸ | MAOB | P27338 | 4/20 | 0.46 |
| ▸ | APP | P05067 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.44 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.44 |
| ▸ | CASP3 | P42574 | 1/20 | 0.44 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9469211 | 1.00 | RAB9A (0.59) | RAB9AALDH1A1SMN1; SMN2LMNAMAPT | |
| SCHEMBL6388039 | 0.91 | APP (0.54) | RAB9AALDH1A1SMN1; SMN2NPC1MAOB | |
| SCHEMBL11614936 | 0.91 | RAB9A (0.69) | RAB9AALDH1A1SMN1; SMN2LMNAMAPT | |
| SCHEMBL23223734 | 0.91 | RAB9A (0.69) | RAB9AALDH1A1SMN1; SMN2LMNAMAPT | |
| SCHEMBL13242652 | 0.91 | APP (0.54) | RAB9AALDH1A1SMN1; SMN2NPC1MAOB | |
| SCHEMBL31453872 | 0.85 | APP (0.48) | RAB9AALDH1A1SMN1; SMN2HPGDNPC1 | |
| SCHEMBL8589028 | 0.84 | RAB9A (0.61) | RAB9AALDH1A1SMN1; SMN2LMNAMAPT | |
| SCHEMBL2849932 | 0.84 | APP (0.59) | RAB9AALDH1A1SMN1; SMN2LMNAMAPT | |
| SCHEMBL865349 | 0.84 | RAB9A (0.71) | RAB9AALDH1A1SMN1; SMN2LMNAMAPT | |
| SCHEMBL21906201 | 0.82 | MAOA (0.72) | RAB9AALDH1A1NPC1TDP1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0597510-B1 | Biologically active reagent prepared from aldehyde-containing polymer, test kit, analytical element and methods of use | JOHNSON & JOHNSON CLIN DIAG (US) | 1998-06-10 | — | — | EP | claimed |
| US-5401633-A | Immunology, label detection | EASTMAN KODAK COMPANY (US) | 1995-03-28 | — | — | US | claimed |