Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | ACACB | O00763 | 2/20 | 0.51 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.50 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.50 |
| ▸ | ABHD6 | Q9BV23 | 2/20 | 0.49 |
| ▸ | MGLL | Q99685 | 1/20 | 0.49 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.49 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.48 |
| ▸ | LIPG | Q9Y5X9 | 2/20 | 0.47 |
| ▸ | LIPC | P11150 | 1/20 | 0.47 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.46 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.46 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.45 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.45 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16217379 | 0.89 | CYP11B2 (0.47) | EPHX2MEN1KMT2ACYP11B1CYP11B2 | |
| SCHEMBL10607268 | 0.88 | EPHX2 (0.59) | EPHX2MEN1KMT2ATP53ACACB | |
| SCHEMBL9900709 | 0.86 | USP30 (0.56) | EPHX2MEN1KMT2ATP53ACACB | |
| SCHEMBL21958728 | 0.86 | TEAD1 (0.59) | EPHX2MEN1KMT2ATP53SLC6A2 | |
| SCHEMBL21958727 | 0.86 | TEAD1 (0.59) | EPHX2MEN1KMT2ATP53SLC6A2 | |
| SCHEMBL2636858 | 0.86 | EPHX2 (0.54) | EPHX2MEN1KMT2ATP53ACACB | |
| SCHEMBL2636860 | 0.85 | EPHX2 (0.53) | EPHX2MEN1KMT2ATP53ACACB | |
| SCHEMBL9903075 | 0.84 | EPHX2 (0.65) | EPHX2MEN1KMT2ATP53SLC6A2 | |
| SCHEMBL10606837 | 0.83 | EPHX2 (0.53) | EPHX2MEN1KMT2ATP53ACACB | |
| SCHEMBL10606827 | 0.82 | EPHX2 (0.64) | EPHX2MEN1KMT2ATP53ACACB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011142359-A1 | SPIRO COMPOUND AND DRUG FOR ACTIVATING ADIPONECTIN RECEPTOR | 日産化学工業株式会社 (JP) | 2011-11-17 | — | — | WO | disclosed |