Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 7/20 | 0.52 |
| ▸ | GABRG2 | P18507 | 7/20 | 0.52 |
| ▸ | GABRB3 | P28472 | 7/20 | 0.52 |
| ▸ | GABRA5 | P31644 | 7/20 | 0.52 |
| ▸ | GABRA3 | P34903 | 7/20 | 0.52 |
| ▸ | GABRA2 | P47869 | 7/20 | 0.52 |
| ▸ | GABRP | O00591 | 6/20 | 0.52 |
| ▸ | GABRD | O14764 | 6/20 | 0.52 |
| ▸ | GABRB1 | P18505 | 6/20 | 0.52 |
| ▸ | GABRB2 | P47870 | 6/20 | 0.52 |
| ▸ | GABRA4 | P48169 | 6/20 | 0.52 |
| ▸ | GABRE | P78334 | 6/20 | 0.52 |
| ▸ | GABRA6 | Q16445 | 6/20 | 0.52 |
| ▸ | GABRG1 | Q8N1C3 | 6/20 | 0.52 |
| ▸ | GABRG3 | Q99928 | 6/20 | 0.52 |
| ▸ | GABRQ | Q9UN88 | 6/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12185210 | 0.82 | MEN1 (0.50) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL31753009 | 0.81 | CYP1A2 (0.57) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL18137605 | 0.81 | CYP1A2 (0.57) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL18137415 | 0.77 | MAPT (0.44) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL31752448 | 0.76 | GABRA2 (0.46) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL31752433 | 0.75 | GABRA2 (0.47) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL19951103 | 0.75 | MAPT (0.46) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL1019601 | 0.74 | CYP1A2 (0.59) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL1233755 | 0.74 | GABRP (0.45) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL28479976 | 0.74 | MAPK1 (0.49) | GABRA1GABRG2GABRB3GABRA5GABRA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011142359-A1 | SPIRO COMPOUND AND DRUG FOR ACTIVATING ADIPONECTIN RECEPTOR | 日産化学工業株式会社 (JP) | 2011-11-17 | — | — | WO | disclosed |