Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16882087 | 0.87 | TGFBR1 (0.87) | TGFBR1CYP3A4 | |
| SCHEMBL2596858 | 0.87 | TGFBR1 (0.87) | TGFBR1CYP3A4 | |
| SCHEMBL2596871 | 0.80 | TGFBR1 (0.73) | TGFBR1CYP3A4 | |
| SCHEMBL2598307 | 0.80 | TGFBR1 (0.73) | TGFBR1CYP3A4 | |
| SCHEMBL2598451 | 0.76 | TGFBR1 (0.75) | TGFBR1CYP3A4 | |
| SCHEMBL2598590 | 0.76 | TGFBR1 (0.85) | TGFBR1CYP3A4 | |
| SCHEMBL2596913 | 0.75 | TGFBR1 (0.76) | TGFBR1CYP3A4 | |
| SCHEMBL2596911 | 0.74 | TGFBR1 (1.00) | TGFBR1CYP3A4 | |
| SCHEMBL2596822 | 0.74 | TGFBR1 (1.00) | TGFBR1CYP3A4 | |
| SCHEMBL2598323 | 0.74 | TGFBR1 (1.00) | TGFBR1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011146287-A1 | PYRAZOLO[4,3-B]PYRIDINE-7-AMINE INHIBITORS OF ALK5 | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2011-11-24 | — | — | WO | disclosed |