⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12286847 | 0.74 | — | — | |
| SCHEMBL18696906 | 0.72 | — | — | |
| SCHEMBL20643267 | 0.69 | — | — | |
| SCHEMBL15459175 | 0.68 | — | — | |
| SCHEMBL13599581 | 0.68 | — | — | |
| SCHEMBL13074380 | 0.68 | — | — | |
| SCHEMBL7151533 | 0.65 | — | — | |
| SCHEMBL6914298 | 0.64 | LMNA (0.45) | — | |
| SCHEMBL15462569 | 0.64 | LMNA (0.45) | — | |
| SCHEMBL2441587 | 0.64 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011143497-A1 | AMINOGLYCOSIDE DERIVATIVES | REMPEX PHARMACEUTICALS, INC. (US) | 2011-11-17 | — | — | WO | disclosed |
| WO-2010132839-A2 | AMINOGLYCOSIDE DOSING REGIMENS | ACHAOGEN, INC. (US) | 2010-11-18 | — | — | WO | disclosed |