Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TERT | O14746 | 2/20 | 0.49 |
| ▸ | TOP1 | P11387 | 2/20 | 0.46 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.45 |
| ▸ | RARB | P10826 | 3/20 | 0.45 |
| ▸ | CYCS | P99999 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.44 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 4/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8031578 | 1.00 | TERT (0.49) | TERTTOP1NR5A1RARBCYCS | |
| SCHEMBL2531376 | 1.00 | TERT (0.49) | TERTTOP1NR5A1RARBCYCS | |
| SCHEMBL12633085 | 0.95 | TERT (0.47) | TERTTOP1NR5A1RARBCYCS | |
| SCHEMBL588821 | 0.94 | TERT (0.44) | TERTTOP1NR5A1RARBCYCS | |
| SCHEMBL584873 | 0.94 | NR5A1 (0.57) | TERTTOP1NR5A1RARBCYCS | |
| SCHEMBL586280 | 0.94 | NR5A1 (0.57) | TERTTOP1NR5A1RARBCYCS | |
| SCHEMBL585100 | 0.94 | NR5A1 (0.57) | TERTTOP1NR5A1RARBCYCS | |
| SCHEMBL584872 | 0.94 | NR5A1 (0.57) | TERTTOP1NR5A1RARBCYCS | |
| SCHEMBL585897 | 0.94 | NR5A1 (0.57) | TERTTOP1NR5A1RARBCYCS | |
| SCHEMBL585218 | 0.94 | TERT (0.44) | TERTTOP1NR5A1RARBCYCS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8030422-B2 | Recoverable polymer-bound homogeneous catalysts for catalytic chain transfer process | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2011-10-04 | — | — | US | disclosed |
| US-20100261851-A1 | Recoverable polymer-bound homogeneous catalysts for catalytic chain transfer process | AXALTA COATING SYSTEMS IP CO. LLC (FORMERLY KNOWN AS U.S. COATINGS IP CO. LLC) | 2010-10-14 | — | — | US | disclosed |