Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TERT | O14746 | 3/20 | 0.47 |
| ▸ | TOP1 | P11387 | 3/20 | 0.45 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.44 |
| ▸ | RARB | P10826 | 3/20 | 0.44 |
| ▸ | CYCS | P99999 | 2/20 | 0.44 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.44 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.42 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 2/20 | 0.42 |
| ▸ | HTR2C | P28335 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8031578 | 0.95 | TERT (0.49) | TERTTOP1NR5A1RARBCYCS | |
| SCHEMBL2531376 | 0.95 | TERT (0.49) | TERTTOP1NR5A1RARBCYCS | |
| SCHEMBL12190732 | 0.95 | TERT (0.49) | TERTTOP1NR5A1RARBCYCS | |
| SCHEMBL585100 | 0.92 | NR5A1 (0.57) | TERTTOP1NR5A1RARBCYCS | |
| SCHEMBL584873 | 0.92 | NR5A1 (0.57) | TERTTOP1NR5A1RARBCYCS | |
| SCHEMBL586280 | 0.92 | NR5A1 (0.57) | TERTTOP1NR5A1RARBCYCS | |
| SCHEMBL584741 | 0.92 | NR5A1 (0.57) | TERTTOP1NR5A1RARBCYCS | |
| SCHEMBL585897 | 0.92 | NR5A1 (0.57) | TERTTOP1NR5A1RARBCYCS | |
| SCHEMBL584872 | 0.92 | NR5A1 (0.57) | TERTTOP1NR5A1RARBCYCS | |
| SCHEMBL585439 | 0.92 | NR5A1 (0.57) | TERTTOP1NR5A1RARBCYCS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8288528-B2 | Meso-substituted porphyrins | L. Molteni & C. Dei Fratelli Alitti—Società di Esercizio S.p.A. (IT) | 2012-10-16 | — | — | US | disclosed |
| US-7947674-B2 | Meso-substituted porphyrins | L. Molteni & C. Dei Fratelli Alitti (IT) | 2011-05-24 | — | — | US | disclosed |
| US-20110112464-A1 | MESO-SUBSTITUTED PORPHYRINS | L. MOLTENI & C. DEI FRATELLI ALITTI SOCIETA DI ESERCIZIO S.P.A. (IT) | 2011-05-12 | — | — | US | disclosed |