Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR2 | O43614 | 1/20 | 0.42 |
| ▸ | LPL | P06858 | 1/20 | 0.42 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | ATM | Q13315 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | IDO1 | P14902 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | MAP2K4 | P45985 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5953905 | 0.94 | ALDH1A1 (0.42) | ALDH1A1TSHRMEN1KMT2ACYP2C19 | |
| SCHEMBL439592 | 0.94 | ALDH1A1 (0.42) | ALDH1A1TSHRMEN1KMT2ACYP2C19 | |
| SCHEMBL15468969 | 0.92 | LPL (0.48) | LPLLIPGALDH1A1TSHRATM | |
| SCHEMBL2632330 | 0.89 | TSHR (0.46) | HCRTR2LPLLIPGPOLBALDH1A1 | |
| SCHEMBL11938108 | 0.89 | TSHR (0.46) | HCRTR2LPLLIPGPOLBALDH1A1 | |
| SCHEMBL13383799 | 0.89 | TSHR (0.46) | HCRTR2LPLLIPGPOLBALDH1A1 | |
| SCHEMBL13383740 | 0.89 | TSHR (0.46) | HCRTR2LPLLIPGPOLBALDH1A1 | |
| SCHEMBL14174106 | 0.88 | MAP2K4 (0.41) | ALDH1A1TSHRMEN1KMT2ACYP2C19 | |
| SCHEMBL14173671 | 0.88 | MAP2K4 (0.41) | ALDH1A1TSHRMEN1KMT2ACYP2C19 | |
| SCHEMBL13308617 | 0.88 | MAP2K4 (0.41) | ALDH1A1TSHRMEN1KMT2ACYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8029958-B2 | Overcoat layer in photoreceptive device | XEROX CORPORATION (US) | 2011-10-04 | — | — | US | disclosed |