Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIPE | Q05469 | 16/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12244 | 0.83 | LIPE (0.34) | LIPE | |
| SCHEMBL1589652 | 0.78 | LIPE (0.56) | LIPE | |
| SCHEMBL1589654 | 0.78 | LIPE (0.56) | LIPE | |
| SCHEMBL12701924 | 0.78 | LIPE (0.56) | LIPE | |
| SCHEMBL12701946 | 0.75 | LIPE (0.48) | LIPE | |
| SCHEMBL10339 | 0.75 | LIPE (0.48) | LIPE | |
| SCHEMBL10340 | 0.75 | LIPE (0.48) | LIPE | |
| SCHEMBL12343 | 0.74 | — | — | |
| SCHEMBL1589136 | 0.71 | LIPE (0.68) | LIPE | |
| SCHEMBL1589660 | 0.71 | LIPE (0.68) | LIPE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011045292-A1 | SPIRO-CONDENSED CYCLOHEXANE DERIVATIVES AS HSL INHIBITORS USEFUL FOR THE TREATMENT OF DIABETES | F. HOFFMANN-LA ROCHE AG (CH) | 2011-04-21 | — | — | WO | disclosed |