Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIPE | Q05469 | 13/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12346 | 0.87 | POLB (0.32) | LIPE | |
| SCHEMBL12194 | 0.83 | LIPE (0.38) | LIPE | |
| SCHEMBL12117 | 0.79 | LIPE (0.33) | LIPE | |
| SCHEMBL11972 | 0.78 | LIPE (0.52) | LIPE | |
| SCHEMBL11971 | 0.78 | LIPE (0.52) | LIPE | |
| SCHEMBL1589420 | 0.74 | LIPE (0.43) | LIPE | |
| SCHEMBL5071 | 0.74 | LIPE (0.43) | LIPE | |
| SCHEMBL1589045 | 0.71 | LIPE (0.57) | LIPE | |
| SCHEMBL1589047 | 0.71 | LIPE (0.57) | LIPE | |
| SCHEMBL12337 | 0.67 | MEN1 (0.35) | LIPE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011045292-A1 | SPIRO-CONDENSED CYCLOHEXANE DERIVATIVES AS HSL INHIBITORS USEFUL FOR THE TREATMENT OF DIABETES | F. HOFFMANN-LA ROCHE AG (CH) | 2011-04-21 | — | — | WO | disclosed |