SCHEMBL12196425

SCHEMBL12196425

CCCC[C@@]1(CC)CS(=O)(=O)c2ccc(F)cc2[C@H](c2cccc(N)c2)[C@@H]1O

nearest known ligand 0.75

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
SLC10A2 Q12908 20/20 0.75

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12196422 1.00 SLC10A2 (0.75) SLC10A2
SCHEMBL12196426 1.00 SLC10A2 (0.75) SLC10A2
SCHEMBL12196428 1.00 SLC10A2 (0.75) SLC10A2
SCHEMBL1361679 0.89 SLC10A2 (0.78) SLC10A2
SCHEMBL6221311 0.87 SLC10A2 (0.86) SLC10A2
SCHEMBL12196590 0.87 SLC10A2 (0.93) SLC10A2
SCHEMBL6827664 0.87 SLC10A2 (0.81) SLC10A2
SCHEMBL19789879 0.87 SLC10A2 (0.66) SLC10A2
SCHEMBL12196461 0.87 SLC10A2 (0.93) SLC10A2
SCHEMBL13619896 0.87 SLC10A2 (0.66) SLC10A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2282991-B1 METHOD FOR THE PRODUCTION OF 1,4-BENZOTHIEPIN-1,1-DIOXIDE DERIVATIVES SANOFI AVENTIS DEUTSCHLAND (DE) 2018-01-24 EP disclosed
US-8461312-B2 Method for the production of 1,4-benzothiepin-1,1-dioxide derivatives SANOFI (FR) 2013-06-11 US disclosed
US-8461312-B2 Method for the production of 1,4-benzothiepin-1,1-dioxide derivatives SANOFI (FR) 2013-06-11 US disclosed
US-20110245486-A1 METHOD FOR THE PRODUCTION OF 1,4-BENZOTHIEPIN-1,1-DIOXIDE DERIVATIVES SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) 2011-10-06 US disclosed
US-20110245486-A1 METHOD FOR THE PRODUCTION OF 1,4-BENZOTHIEPIN-1,1-DIOXIDE DERIVATIVES SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) 2011-10-06 US disclosed
WO-2009132832-A2 METHOD FOR THE PRODUCTION OF 1,4-BENZOTHIEPIN-1,1-DIOXIDE DERIVATIVES SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) 2009-11-05 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110245486-A1 METHOD FOR THE PRODUCTION OF 1,4-BENZOTHIEPIN-1,1-DIOXIDE DERIVATIVES BBOX1, SULT1E1, PTGS1 SLC10A2 4461/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.