SCHEMBL12196494

SCHEMBL12196494

COC(=O)NCCOCCOCCNC(=O)C(CCCCC1CC1)C1CC1

nearest known ligand 0.38

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
▸ MEN1 O00255 1/20 0.38
▸ KMT2A Q03164 1/20 0.38
▸ NAAA Q02083 3/20 0.31
▸ EPHX1 P07099 2/20 0.31
▸ TLR2 O60603 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12196503 0.89 MEN1 (0.39) MEN1KMT2ATLR2
SCHEMBL12196496 0.87 MEN1 (0.36) MEN1KMT2ATLR2
SCHEMBL15256876 0.86 EPHX2 (0.36) MEN1KMT2ANAAA
SCHEMBL15256893 0.81 SIRT6 (0.42) TLR2
SCHEMBL12706033 0.72 MEN1 (0.34) MEN1KMT2ATLR2
SCHEMBL8396346 0.71 EPHX1 (0.52) MEN1KMT2AEPHX1
SCHEMBL12706048 0.68 MEN1 (0.38) MEN1KMT2AEPHX1TLR2
SCHEMBL12705941 0.68 EPHX1 (0.50) MEN1KMT2AEPHX1TLR2
SCHEMBL8397010 0.68 EPHX1 (0.45) EPHX1
SCHEMBL9340071 0.67 EPHX1 (0.52) MEN1KMT2AEPHX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8729030-B2 Peptides that bind to the erythropoietin receptor AFFYMAX, INC. (US) 2014-05-20 — — US disclosed
US-20130244939-A1 NOVEL PEPTIDES THAT BIND TO THE ERYTHROPOIETIN RECEPTOR AFFYMAX, INC. (US) 2013-09-19 — — US disclosed
US-20130079283-A1 Erythropoitein Receptor Peptide Formulations and Uses AFFYMAX, INC. (US) 2013-03-28 — — US disclosed
US-20110245176-A1 NOVEL PEPTIDES THAT BIND TO THE ERYTHROPOIETIN RECEPTOR AFFYMAX, INC. (US) 2011-10-06 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130244939-A1 NOVEL PEPTIDES THAT BIND TO THE ERYTHROPOIETIN RECEPTOR EPOR, PROKR1, EDNRB MEN1 3831/4885KMT2A 4517/4885NAAA 4650/4885
US-20110245176-A1 NOVEL PEPTIDES THAT BIND TO THE ERYTHROPOIETIN RECEPTOR EPOR, PROKR1, EDNRB MEN1 3831/4885KMT2A 4517/4885NAAA 4650/4885
US-20130079283-A1 Erythropoitein Receptor Peptide Formulations and Uses EPOR, MPL, PROKR1 MEN1 1252/4885KMT2A 3761/4885NAAA 4392/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback