Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 18/20 | 0.55 |
| ▸ | ADORA2A | P29274 | 12/20 | 0.55 |
| ▸ | ADORA1 | P30542 | 8/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10156160 | 0.92 | ADORA3 (0.55) | ADORA3ADORA2AADORA1 | |
| SCHEMBL1412177 | 0.89 | ADORA2A (0.57) | ADORA3ADORA2AADORA1 | |
| SCHEMBL293365 | 0.89 | ADORA2A (0.57) | ADORA3ADORA2AADORA1 | |
| SCHEMBL1833926 | 0.89 | ADORA2A (0.57) | ADORA3ADORA2AADORA1 | |
| SCHEMBL1412247 | 0.89 | ADORA2A (0.57) | ADORA3ADORA2AADORA1 | |
| SCHEMBL1412175 | 0.89 | ADORA2A (0.57) | ADORA3ADORA2AADORA1 | |
| SCHEMBL239591 | 0.89 | ADORA2A (0.57) | ADORA3ADORA2AADORA1 | |
| SCHEMBL1833924 | 0.89 | ADORA2A (0.57) | ADORA3ADORA2AADORA1 | |
| SCHEMBL239273 | 0.89 | ADORA2A (0.65) | ADORA3ADORA2AADORA1 | |
| SCHEMBL3026443 | 0.88 | ADORA3 (0.57) | ADORA3ADORA2AADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2018388-B9 | BISADENOSINE COMPOUNDS AS ADENOSINE A2A RECEPTOR AGONISTS | NOVARTIS AG (CH) | 2011-10-05 | — | — | EP | disclosed |
| EP-2018388-B1 | BISADENOSINE COMPOUNDS AS ADENOSINE A2A RECEPTOR AGONISTS | NOVARTIS AG (CH) | 2011-03-16 | — | — | EP | disclosed |
| WO-2007121924-A2 | BISADENOSINE COMPOUNDS AS ADENOSINE A2A RECEPTOR AGONISTS | NOVARTIS AG (CH) | 2007-11-01 | — | — | WO | disclosed |