Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12197818 | 0.75 | CYP19A1 (0.36) | — | |
| SCHEMBL8081279 | 0.64 | CYP3A4 (0.37) | CYP3A4TSHRMAPK1 | |
| SCHEMBL4070655 | 0.62 | ALDH1A1 (0.37) | CYP3A4TSHR | |
| SCHEMBL4067017 | 0.61 | CYP19A1 (0.41) | — | |
| SCHEMBL29362737 | 0.61 | ALDH1A1 (0.47) | CYP3A4TSHRMAPK1 | |
| SCHEMBL30030734 | 0.61 | MEN1 (0.47) | CYP3A4TSHRMAPK1 | |
| SCHEMBL1027495 | 0.61 | MEN1 (0.47) | CYP3A4TSHRMAPK1 | |
| SCHEMBL3344312 | 0.61 | ALDH1A1 (0.47) | CYP3A4TSHRMAPK1 | |
| SCHEMBL2789554 | 0.59 | AR (0.45) | — | |
| SCHEMBL16253981 | 0.57 | MAPT (0.51) | CYP3A4TSHRMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2144506-B1 | 3-SUBSTITUTED-[1,2,3]-BENZOTRIAZINONE COMPOUND FOR ENHANCING GLUTAMATERGIC SYNAPTIC RESPONSES | CORTEX PHARMA INC (US) | 2011-10-05 | — | — | EP | disclosed |