Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 7/20 | 0.34 |
| ▸ | HTR2C | P28335 | 2/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | METAP1 | P53582 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | PDE4A | P27815 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4067017 | 0.83 | CYP19A1 (0.41) | CYP19A1GRIA2MAOBHTR2CHTR2A | |
| SCHEMBL12197814 | 0.75 | CYP3A4 (0.31) | — | |
| SCHEMBL14147757 | 0.68 | MAOB (0.35) | CYP19A1MAOBHTR2CNPC1 | |
| SCHEMBL16369469 | 0.67 | CYP19A1 (0.46) | CYP19A1MAOBNPC1 | |
| SCHEMBL14647199 | 0.66 | MEN1 (0.37) | GRIA2 | |
| SCHEMBL26714218 | 0.66 | MAOB (0.40) | CYP19A1MAOBMETAP1NPC1 | |
| SCHEMBL19197254 | 0.64 | CYP19A1 (0.44) | CYP19A1MAOBNPC1 | |
| SCHEMBL15865719 | 0.64 | CYP19A1 (0.35) | CYP19A1MAOBNPC1PDE4A | |
| SCHEMBL18218827 | 0.62 | HTR2A (0.52) | GRIA2HTR2CHTR2AHTR2BMETAP1 | |
| SCHEMBL14647203 | 0.62 | CHRM2 (0.38) | GRIA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2144506-B1 | 3-SUBSTITUTED-[1,2,3]-BENZOTRIAZINONE COMPOUND FOR ENHANCING GLUTAMATERGIC SYNAPTIC RESPONSES | CORTEX PHARMA INC (US) | 2011-10-05 | — | — | EP | disclosed |