Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.33 |
| ▸ | SIRT2 | Q8IXJ6 | 10/20 | 0.33 |
| ▸ | LCK | P06239 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12329477 | 1.00 | HDAC6 (0.34) | HDAC6HDAC1POLBNLRP3SIRT2 | |
| SCHEMBL4361738 | 0.89 | POLB (0.38) | HDAC6HDAC1POLBSIRT2 | |
| SCHEMBL29103272 | 0.87 | HDAC6 (0.36) | HDAC6HDAC1POLBNLRP3SIRT2 | |
| SCHEMBL9847306 | 0.86 | MEN1 (0.34) | HDAC6HDAC1SIRT2ATM | |
| SCHEMBL201190 | 0.85 | CPB2 (0.42) | — | |
| SCHEMBL2059164 | 0.85 | HDAC6 (0.36) | HDAC6HDAC1POLBNLRP3SIRT2 | |
| SCHEMBL12765185 | 0.85 | HDAC6 (0.36) | HDAC6HDAC1POLBNLRP3SIRT2 | |
| SCHEMBL201189 | 0.85 | CPB2 (0.42) | — | |
| SCHEMBL17484674 | 0.85 | CPB2 (0.32) | — | |
| Hydrochloric Acid SCHEMBL9876601 | 0.84 | HDAC6 (0.35) | HDAC6HDAC1NLRP3SIRT2ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2371421-A1 | Ligands of insulin degrading enzyme and their uses | Université de Lille 2 Droit et Santé (FR) | 2011-10-05 | — | — | EP | disclosed |