Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | SIRT2 | Q8IXJ6 | 14/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12329477 | 0.86 | HDAC6 (0.34) | SIRT2HDAC6HDAC1ATM | |
| SCHEMBL12199029 | 0.86 | HDAC6 (0.34) | SIRT2HDAC6HDAC1ATM | |
| SCHEMBL365025 | 0.86 | CPB2 (0.37) | — | |
| SCHEMBL29103272 | 0.84 | HDAC6 (0.36) | MEN1KMT2ASIRT2HDAC6HDAC1 | |
| SCHEMBL4361738 | 0.84 | POLB (0.38) | SIRT2HDAC6HDAC1 | |
| SCHEMBL2471875 | 0.84 | OPRK1 (0.40) | MEN1KMT2AHDAC6HDAC1 | |
| SCHEMBL2471870 | 0.84 | OPRK1 (0.40) | MEN1KMT2AHDAC6HDAC1 | |
| SCHEMBL2059164 | 0.83 | HDAC6 (0.36) | MEN1KMT2ASIRT2HDAC6HDAC1 | |
| SCHEMBL12765185 | 0.83 | HDAC6 (0.36) | MEN1KMT2ASIRT2HDAC6HDAC1 | |
| SCHEMBL2059178 | 0.82 | SIRT2 (0.48) | MEN1KMT2ASIRT2ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0412595-A1 | Antiherpetic agents | MERCK & CO. INC. (US) | 1991-02-13 | — | — | EP | disclosed |