Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 9/20 | 0.59 |
| ▸ | ESR2 | Q92731 | 9/20 | 0.59 |
| ▸ | ESRRG | P62508 | 4/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.59 |
| ▸ | AR | P10275 | 1/20 | 0.59 |
| ▸ | HPGD | P15428 | 1/20 | 0.59 |
| ▸ | TSHR | P16473 | 1/20 | 0.59 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.59 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.59 |
| ▸ | HTR6 | P50406 | 1/20 | 0.59 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | TYR | P14679 | 1/20 | 0.43 |
| ▸ | SHBG | P04278 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10204706 | 0.84 | MAPT (0.55) | ESR1ESR2ESRRGCYP3A4HSD17B10 | |
| SCHEMBL8386480 | 0.79 | ESR1 (0.67) | ESR1ESR2ESRRGCYP3A4HSD17B10 | |
| SCHEMBL12199599 | 0.78 | ESR1 (0.50) | ESR1ESR2ESRRGCYP3A4HSD17B10 | |
| Bisphenol A SCHEMBL4231382 | 0.78 | ESR1 (0.80) | ESR1ESR2ESRRGCYP3A4HSD17B10 | |
| Bisphenol A SCHEMBL1557174 | 0.78 | ESR1 (0.80) | ESR1ESR2ESRRGCYP3A4HSD17B10 | |
| Bisphenol A SCHEMBL30041667 | 0.77 | ESR1 (0.89) | ESR1ESR2ESRRGCYP3A4HSD17B10 | |
| Bisphenol A SCHEMBL766397 | 0.77 | ESR1 (0.89) | ESR1ESR2ESRRGCYP3A4HSD17B10 | |
| SCHEMBL3419256 | 0.77 | SHBG (0.53) | ESR1ESR2ESRRGCYP3A4HSD17B10 | |
| SCHEMBL27996 | 0.77 | ESR1 (1.00) | ESR1ESR2ESRRGCYP3A4HSD17B10 | |
| Bisphenol A SCHEMBL3170263 | 0.77 | ESR1 (1.00) | ESR1ESR2ESRRGCYP3A4HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2374832-A1 | Addition curable self-adhesive silicone rubber composition | Shin-Etsu Chemical Co., Ltd. (JP) | 2011-10-12 | — | — | EP | disclosed |