Thonzylamine

Thonzylamine

SCHEMBL121996

COc1ccc(CN(CCN(C)C)c2ncccn2)cc1

nearest known ligand 0.97

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 4/20 0.97
MAPT P10636 1/20 0.97
TSHR P16473 4/20 0.77
CYP1A2 P05177 3/20 0.77
CYP2D6 P10635 3/20 0.77
CHRM2 P08172 3/20 0.77
ADRA2A P08913 3/20 0.77
DRD1 P21728 3/20 0.77
SLC6A4 P31645 3/20 0.77
SLC6A3 Q01959 3/20 0.77
KCNH2 Q12809 3/20 0.77
ALDH1A1 P00352 3/20 0.77
HTR2A P28223 2/20 0.77
HRH1 P35367 2/20 0.77
CYP2C19 P33261 2/20 0.77
OPRM1 P35372 2/20 0.77
MEN1 O00255 1/20 0.77
CYP3A4 P08684 1/20 0.77
HTR1A P08908 1/20 0.77
HTR2C P28335 1/20 0.77

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Thonzylamine SCHEMBL29417 0.98 LMNA (1.00) LMNAMAPTTSHRCYP1A2CYP2D6
Thonzylamine SCHEMBL1650305 0.98 LMNA (0.94) LMNAMAPTTSHRCYP1A2CYP2D6
Pyrilamine SCHEMBL28086659 0.91 LMNA (0.95) LMNAMAPTTSHRCYP1A2CYP2D6
SCHEMBL28298127 0.89 LMNA (0.77) LMNAMAPTTSHRCYP1A2CYP2D6
Pyrilamine SCHEMBL4075657 0.88 LMNA (0.90) LMNAMAPTTSHRCYP1A2CYP2D6
SCHEMBL17817354 0.88 LMNA (0.76) LMNAMAPTTSHRCYP1A2CYP2D6
Pyrilamine SCHEMBL29444024 0.87 LMNA (1.00) LMNAMAPTTSHRCYP1A2CYP2D6
Pyrilamine SCHEMBL19114 0.87 LMNA (1.00) LMNAMAPTTSHRCYP1A2CYP2D6
Pyrilamine SCHEMBL22118219 0.86 LMNA (0.97) LMNAMAPTTSHRCYP1A2CYP2D6
Pyrilamine SCHEMBL28823277 0.86 LMNA (0.97) LMNAMAPTTSHRCYP1A2CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1455 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4731194-A1 MATERIALS AND METHODS FOR MITIGATING THE PRESENCE OF NITROSAMINES IN PACKAGING USING AN ACTIVE AGENT CSP Technologies, Inc. (US) 2026-04-29 EP claimed
EP-4704971-A1 GAMMA STIMULATION AND NEUROMODULATOR COMBINATION THERAPY Cognito Therapeutics, Inc. (US) 2026-03-11 EP claimed
EP-4691492-A2 LIQUID COMPOSITIONS Kenvue Brands LLC (US) 2026-02-11 EP claimed
WO-2025264260-A1 MATERIALS AND METHODS FOR MITIGATING THE PRESENCE OF NITROSAMINES IN PACKAGING USING AN ACTIVE AGENT CSP TECHNOLOGIES, INC. (US) 2025-12-26 WO claimed
EP-4154879-B1 PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING NICOTINE WITHDRAWAL SYMPTOMS KOREA INST SCI & TECH (KR) 2025-09-10 EP claimed
WO-2025111482-A1 COMPLEXING AGENT SALT FORMULATIONS OF PHARMACEUTICAL COMPOUNDS AT LOW STOICHIOMETRIC RATIOS BEXSON BIOMEDICAL, INC. (US) 2025-05-30 WO claimed
CN-115219862-B Space arc fault detection method, system and storage medium 哈尔滨工业大学(深圳) 2025-05-06 CN claimed
WO-2024263560-A1 MATERIALS AND METHODS FOR MITIGATING THE PRESENCE OF NITROSAMINES IN PACKAGING USING AN ACTIVE AGENT CSP TECHNOLOGIES, INC. (US) 2024-12-26 WO claimed
WO-2024229174-A1 GAMMA STIMULATION AND NEUROMODULATOR COMBINATION THERAPY Cognito Therapeutics, Inc. (US) 2024-11-07 WO claimed
CN-112163592-B Method for recognizing and early warning pedestrian state by using mobile phone and smart phone thereof 江苏大学 2024-05-14 CN claimed
WO-2007026151-A1 ANTIHISTAMINE- AND CORTICOSTEROID- CONTAINING LIPOSOME COMPOSITION AND ITS USE FOR THE MANUFACTURE OF A MEDICAMENT FOR TREATING RHINITIS AND RELATED DISORDERS BIOLIPOX AB (SE) 2007-03-08 WO claimed
WO-2006131737-A2 METHOD AND COMPOSITION FOR TREATING INFLAMMATORY DISORDERS BIOLIPOX AB (SE) 2006-12-14 WO claimed
US-20060057205-A1 Phenylepherine containing dosage form SOVEREIGN PHARMACEUTICALS, LTD. (US) 2006-03-16 US claimed
WO-2006022996-A2 DOSAGE FORM CONTAINING MULTIPLE DRUGS SOVEREIGN PHARMACEUTICALS, LTD. (US) 2006-03-02 WO claimed
US-20050266032-A1 Dosage form containing multiple drugs SOVEREIGN PHARMACEUTICALS, LTD. (US) 2005-12-01 US claimed
WO-2005094832-A1 COMPOSITIONS COMPRISING MELOXICAM BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2005-10-13 WO claimed
EP-1336602-A1 Nitrate prodrugs able to release nitric oxide in a controlled and selective way and their use for prevention and treatment of inflammatory, ischemic and proliferative diseases Scaramuzzino, Giovanni (IT) 2003-08-20 EP claimed
EP-0517160-B1 Extended-release ophthalmic preparations INVERNI DELLA BEFFA SPA (IT) 1996-03-13 EP claimed
US-5183665-A Using antihistamine NITTO DENKO CORPORATION (JP) 1993-02-02 US claimed
EP-0517160-A1 Extended-release ophthalmic preparations INVERNI DELLA BEFFA S.P.A. (IT) 1992-12-09 EP claimed