Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 5/20 | 0.52 |
| ▸ | RAB9A | P51151 | 5/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.38 |
| ▸ | MEN1 | O00255 | 5/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.38 |
| ▸ | CASP1 | P29466 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | APAF1 | O14727 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | CASP7 | P55210 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.36 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12199851 | 0.87 | NPC1 (0.52) | NPC1RAB9APOLBLMNAKDM4E | |
| SCHEMBL12199836 | 0.82 | NPC1 (0.58) | NPC1RAB9APOLBLMNAKDM4E | |
| SCHEMBL12199835 | 0.80 | NPC1 (0.54) | NPC1RAB9APOLBLMNAKDM4E | |
| SCHEMBL8017347 | 0.77 | NPC1 (0.58) | NPC1RAB9APOLBLMNAKDM4E | |
| SCHEMBL29491989 | 0.77 | NPC1 (0.58) | NPC1RAB9APOLBLMNAKDM4E | |
| SCHEMBL7703339 | 0.75 | NPC1 (0.71) | NPC1RAB9APOLBLMNAKDM4E | |
| SCHEMBL9408821 | 0.74 | NPC1 (0.56) | NPC1RAB9APOLBLMNAKDM4E | |
| Bumetrizole SCHEMBL6068328 | 0.74 | NPC1 (0.60) | NPC1RAB9APOLBLMNAKDM4E | |
| SCHEMBL15910157 | 0.73 | NPC1 (0.55) | NPC1RAB9APOLBLMNAKDM4E | |
| Bumetrizole SCHEMBL8603228 | 0.72 | NPC1 (0.53) | NPC1RAB9APOLBLMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8034878-B2 | Low molecular weight ethylene interpolymers, methods of making, and uses thereof | DOW GLOBAL TECHNOLOGIES LLC (US) | 2011-10-11 | — | — | US | disclosed |
| US-20080306217-A1 | Low Molecular Weight Ethylene Interpolymers, Methods of Making, and Uses Thereof | DOW GLOBAL TECHNOLOGIES LLC | 2008-12-11 | — | — | US | disclosed |
| US-7259219-B2 | Low molecular weight copolymer of ethylene and vinyl aromatic monomer and uses thereof | DOW GLOBAL TECHNOLOGIES INC. (US) | 2007-08-21 | — | — | US | disclosed |
| WO-2007078697-A1 | LOW MOLECULAR WEIGHT ETHYLENE INTERPOLYMERS, METHODS OF MAKING, AND USES THEREOF | DOW GLOBAL TECHNOLOGIES INC. (US) | 2007-07-12 | — | — | WO | disclosed |