Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 9/20 | 0.71 |
| ▸ | RAB9A | P51151 | 9/20 | 0.71 |
| ▸ | LMNA | P02545 | 1/20 | 0.63 |
| ▸ | POLB | P06746 | 2/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.48 |
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | HPGD | P15428 | 5/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | IGF2BP2 | Q9Y6M1 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | TDO2 | P48775 | 1/20 | 0.35 |
| ▸ | IDO2 | Q6ZQW0 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1275936 | 0.86 | NPC1 (0.71) | NPC1RAB9ALMNAPOLBSMN1; SMN2 | |
| SCHEMBL110113 | 0.86 | NPC1 (0.71) | NPC1RAB9ALMNAPOLBSMN1; SMN2 | |
| SCHEMBL29489567 | 0.86 | NPC1 (0.71) | NPC1RAB9ALMNAPOLBSMN1; SMN2 | |
| SCHEMBL18375849 | 0.83 | NPC1 (0.68) | NPC1RAB9ALMNAPOLBSMN1; SMN2 | |
| SCHEMBL10598824 | 0.83 | NPC1 (1.00) | NPC1RAB9ALMNAPOLBSMN1; SMN2 | |
| SCHEMBL9408736 | 0.83 | NPC1 (0.68) | NPC1RAB9ALMNAPOLBSMN1; SMN2 | |
| SCHEMBL105385 | 0.83 | NPC1 (0.68) | NPC1RAB9ALMNAPOLBSMN1; SMN2 | |
| SCHEMBL31267541 | 0.82 | NPC1 (0.66) | NPC1RAB9ALMNAPOLBSMN1; SMN2 | |
| SCHEMBL20365734 | 0.82 | NPC1 (0.66) | NPC1RAB9ALMNAPOLBSMN1; SMN2 | |
| SCHEMBL258759 | 0.82 | NPC1 (0.66) | NPC1RAB9ALMNAPOLBSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6344505-B1 | Mono- and bis-benzotriazolyldihydroxybiaryl UV absorbers | CYTEC INDUSTRIES INC. | 2002-02-05 | — | — | US | disclosed |